ebstein's anomaly is defined as the significant apical displacement of the tricuspid valve causing tricuspid regurgitation. although a variety of concomitant lesions have been previously described, we herein introduce an unusual presentation.  our patient was an 86-year-old man with a primary presentation of typical chest pain in the setting of recently diagnosed coronary artery disease with co...

Let$ P_{n}(x)= sum_{i=0}^{n} A_{i}x^{i}$ be a random algebraicpolynomial, where $A_{0},A_{1}, cdots $ is a sequence of independent random variables belong to the domain of attraction of the normal law. Thus $A_j$'s for $j=0,1cdots $ possesses the characteristic functions $exp {-frac{1}{2}t^{2}H_{j}(t)}$, where $H_j(t)$'s are complex slowlyvarying functions.Under the assumption that there exist ...

let$ p_{n}(x)= sum_{i=0}^{n} a_{i}x^{i}$ be a random algebraicpolynomial, where $a_{0},a_{1}, cdots $ is a sequence of independent random variables belong to the domain of attraction of the normal law. thus $a_j$'s for $j=0,1cdots $ possesses the characteristic functions $exp {-frac{1}{2}t^{2}h_{j}(t)}$, where $h_j(t)$'s are complex slowlyvarying functions.under the assumption that th...

The objective of this study was to identify a potential mechanism for S-nitrosation of proteins. Therefore, we assessed S-nitrosation of bovine serum albumin by dinitrosyl-iron-di-L-cysteine complex [(NO)2Fe(L-cysteine)2], a compound similar to naturally occurring iron-nitrosyls. Within 5-10 min, (NO)2Fe(L-cysteine)2 generated paramagnetic albumin-bound dinitrosyl-iron complex and S-nitrosoalbu...

The Anaphase-Promoting Complex/Cyclosome (APC/C) is an essential ubiquitin ligase that targets numerous proteins for proteasome-mediated degradation in mitosis and G1. To gain further insight into cellular pathways controlled by APC/C(Cdh1), we developed two complementary approaches to identify additional APC/C(Cdh1) substrates in budding yeast. First, we analyzed the stabilities of proteins th...

The complexity of monitoring and controlling a large scale system, such as a communication network, is considered. Relevant literature is reviewed, with emphasis on both behavioral and non-behavioral approaches to measuring complexity. A simulated large scale network is described that is used in an experiment to assess the effect of network redundancy and number of system levels on human fault ...

The dynamic nature of web data brings forward the need for maintaining data versions as well as identifying semantically rich changes between them. In this paper, we advocate the need for supporting complex changes in evolving RDF(S) knowledge bases. We outline the basic challenges and provide solution insights through a real-world example from the field of biology.

Signaling pathways enable cells to sense and respond to their environment. Many cellular signaling strategies are conserved from fungi to humans, yet their activity and phenotypic consequences can vary extensively among individuals within a species. A systematic assessment of the impact of naturally occurring genetic variation on signaling pathways remains to be conducted. In S. cerevisiae, bot...

The assembly of the yeast transcription factors IIIA, IIIB, and IIIC, represented by crude chromatographic fractions, into a stable complex on the 5 S RNA gene has been assessed using a template competition assay (Bogenhagen, D. F., Wormington, W. M., and Brown, D. D. (1982) Cell 28, 413-421). The yeast factor A can interact transiently with the yeast 5 S RNA gene, but both factors A and C are ...