Background SAPHO is a heterogeneous autoinflammatory disease, characterized by bone and joint involvement wide variety of dermatologic manifestations, including palmo-plantar pustulosis (PPP), acne, hidradenitis suppurativa (HS), pyoderma gangrenosum (PG), psoriasis, Snedd-Wilkinson disease Sweet syndrome. In children, the osteo-articular manifestations are chronic recurrent multifocal osteomye...

Fig. 2 A 41-year-old man who suffered from pain in several joints for more than 10 years was referred for a bone scintigraphy. The patient was treated with non-steroidal anti-inflammatory drugs, but this treatment regimen did not result in a reduction of symptoms. Upon completion of the physical examination, no remarkable findings were noted. All routine laboratory tests were normal. The images...

les figures mythiques ou légendaires s’adaptent à chaque époque et en chaque lieu. cet article tente de montrer comment constance pipelet, future princesse de salm (1767-1845), une des filles des lumières et admiratrice des idéaux de la révolution française, se sert du récit de la vie de sapho, grande poétesse de l’antiquité, pour proposer une sapho qui est aussi amoureuse, éplorée et trahie qu...

A 68-year-old woman with a history of breast cancer, who had undergone left quadrantectomy 24 years prior, had suffered from palmoplantar pustulosis (PPP) and pain in multiple joints and bones for 3 years. Technetium bone scanning showed increased uptake in the sternum, sternocostoclavicular joint, cervical vertebrae, lumbar vertebrae, and right knee (Picture 1, left). A radiograph of the lumba...

Periodic fever syndromes are a group of diseases characterized by episodes of fever with healthy intervals between febrile episodes. In the first part of this paper, we presented a guideline for approaching patients with periodic fever and reviewed two common disorders with periodic fever in Iranian patients including familial Mediterranean fever (FMF) and periodic fever syndromes except for pe...