نتایج جستجو برای: sarcoma tumors
تعداد نتایج: 244044 فیلتر نتایج به سال:
This is the report of a mandibular neuroectodermal/ewing sarcoma in an 8-year-old male cross breed dogthat is unique because of tumor origin location. Pedunculated, ulcerative, firm 6.0 × 4.0 × 5.5 cm tumor masseffaced the bone at the rostral part of the mandible and had a white-sanguineous color at cross sectionappearance. Histopathologically, small round blue cell tumor was diagnosed. Immunoh...
The Ewing sarcoma family of tumors (EFT) is a group of highly malignant small round blue cell tumors occurring in children and young adults. We report here the largest genomic survey to date of 101 EFT (65 tumors and 36 cell lines). Using a combination of whole genome sequencing and targeted sequencing approaches, we discover that EFT has a very low mutational burden (0.15 mutations/Mb) but fre...
OBJECTIVES EWS/FLI-1 fusion mainly appears in Ewing's sarcoma or the primitive neuroectodermal tumors and represents a genomic marker for these tumors. However, it can appear with lower frequency in other soft tissue tumors. The paper investigates the presence of EWS/FLI-1 fusion in clinically diagnosed sarcoma belonging to different non-Ewing connective tissue tumors in order to search for a p...
Soft tissue sarcoma (STS) most often occurs sporadically, but can also arise in the setting of a germline cancer predisposition syndrome (CPS). There is significant diversity amongst STS diagnoses as these tumors exhibit variety histologies, occur all age groups, and any location body. This reflected many known associated associations. Some diagnoses, such anaplastic rhabdomyosarcoma, are with ...
Sarcomas are a biologically complex group of tumors of mesenchymal origin. By using gene expression microarray analysis, we aimed to find clues into the cellular differentiation and oncogenic pathways active in these tumors as well as potential biomarkers and therapeutic targets. We examined 181 tumors representing 16 classes of human bone and soft tissue sarcomas on a 12,601-feature cDNA micro...
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