Soft tissue sarcomas are a group of rare malignant tumors with high recurrence and mortality rate. Little progress has been made in the treatment this pathology over past decades. Surgery or without adjuvant/neoadjuvant radiotherapy is still first-line therapy for localized soft sarcomas, chemotherapy an additional option high-risk patients. However, not all patients advanced metastatic benefit...

Undifferentiated sarcomas, more correctly known as undifferentiated pleomorphic sarcomas (UPS), are a form of soft tissue sarcoma. They appear to be uncommonly diagnosed in veterinary species but represent the second most common sarcoma human adults. There is an evolving nomenclature around these tumours, with older reports referring ‘malignant fibrous histiocytoma’, have been reclassified into...

progression of mouse sarcoma. The results indicated that adiponectin deficiency increased the tumor incidence; in addition, the occurrence of sarcoma was earlier in contrast with the wild type (WT) mice. It is worth mentioning, after the sarcomas formation, adiponectin deficiency had been shown to have the effect of suppressing tumor growth. Mortality rates of the adiponectin-deficient mice wit...

Although benign hemangiomas are among the most common diagnoses among connective tissue tumors, angiosarcomas and other sarcomas arising from blood vessels are rare, even among sarcomas. Because endothelial tumors have unique embryonal derivation compared with other sarcomas, it is not surprising they have unique characteristics. Herein are reviewed some of these unique characteristics and ther...

A commercially available polyclonal antiserum (Dakopatts) raised against bovine neuron specific enolase (NSE) was reacted with 197 sarcomas, 32 carcinomas, 11 carcinoid tumours and 20 malignant melanomas to assess its specificity for neuroendocrine tumours. All the tumours had been fixed in formalin and embedded in paraffin. Positive tumour cells were found in two of 11 squamous cell carcinomas...

Synovial sarcomas are most frequently observed in the extremities. Although synovial sarcomas are the third most common histological type of soft-tissue sarcomas of the extremities, primary mediastinal synovial sarcoma is extremely rare. Monophasic synovial sarcoma is the most commonly observed subtype. whereas the biphasic subtype is less common. We present our case which was diagnosed as biph...

Chest wall contains a wide array of tissues ranging from soft tissues like skin and muscle to bone. A variety of sarcomas can present with a painful or painless mass, which often requires histological testing for diagnosis. Chest wall sarcomas are very rare entities which are often growing slow . A multidisciplinary team is necessary for the management of chest wall sarcomas. We present a case ...

The role of FDG PET/CT in management of soft tissue and bone sarcomas has been described in many studies up-to-date. However, contribution of PET/CT to diagnosis and treatment in some types of sarcomas that are seen with low incidence has not been identified properly yet. Clear cell sarcoma, synovial sarcoma of chest and myxoid lyposarcoma are rare types of sarcomas. We aimed to describe the FD...

Breast sarcomas are rare neoplasms arising from the few epithelial elements of the gland. It represents much <1% of all breast cancer. Of the heterogeneous group of sarcomas, the more common subtypes include spindle cell sarcoma. The main risk factor for the development of breast sarcomas is previous radiation therapy following breast-conservation surgery for breast cancer or non-Hodgkin's lymp...

Sarcomas are rare tumors account for about 1% of cancers in adult. Soft tissue sarcomas are the most common one. Synovial sarcoma's incident is about 10% of all sarcomas and most commonly rise from para-articular regions in young adults. Based on our knowledge there have been only two reports of thyroid synovial sarcoma in medical literature. We report a 44-year old woman presented with a rapid...