Objective: Patients with mesial temporal lobe epilepsy (MTLE) may present unstable pattern of seizures. We aimed to evaluate the occurrence of relapse-remitting seizures in MTLE with (MTLE-HS) and without (MTLE-NL) hippocampal sclerosis. Method: We evaluated 172 patients with MTLE-HS (122) or MTLE-NL (50). Relapse-remitting pattern was defined as periods longer than two years of seizure-freedom...

how to cite this article: ghofrani m. lysosomal storage disease (lsds). iran j child neurol. 2015 autumn;9:4(suppl.1): 1. pls see pdf.

background there are few reports from iran about the epidemiology and clinical features of inflammatory bowel disease (ibd). this study aims to determine the epide­miologic profile and clinical features of ibd in northwest iran referral centers. methods in a cross-sectional setting, we evaluated 200 patients with definitive diagno­ses of ibd who referred to tabriz educational hospitals during t...

conclusions in cases of unusual vascular lesions, metabolic diseases must be considered. in homocystinuria, early diagnosis and treatment are important. blood homocysteine levels can be returned to normal, and some complications can be prevented. introduction homocystinuria is a hereditary disease caused by a defect in the enzymes involved in metabolizing methionine. homocystinuria can influenc...

thrombin is a multifunctional enzyme which has key roles in coagulation cascade and inflammatory events. the pro-inflammatory functions of thrombin occur by different mechanisms including increasing mast cell degranulation, up-regulating the expression of cell adhesion molecules (cams) and promoting the secretion of inflammatory chemokines and cytokines. dysregulated signaling functions of thro...

Forsyth, C. C., Forbes, M., and Cumings, J. N. (1971). Archives of Disease in Childhood, 46, 273. Adrenocortical atrophy and diffuse cerebral sclerosis. A boy, diagnosed as having Addison's disease due to idiopathic atrophy of the adrenal glands at the age of 7 years, developed the first evidence of what was originally thought to be 'Schilder's disease' at 8 years and 10 months. He died at 9 ye...

how to cite this article: karimzadeh p. pelizaeus-merzbacher- disease (pmd) and pelizaeus-merzbacher-like disease (pmld). iran j child neurol autumn 2014;8:4 (suppl.1):9-10.   pls see pdf.

We read with great interest the paper by Schilder and colleagues on citrate anticoagulation versus systemic heparinisation (CASH) [1] and its related commentary [2], but would like to comment on two important metabolic issues. First, in-circuit ionized calcium was not monitored in the CASH trial. Keeping postfilter ionized calcium within tight limits, however, results in more optimal anticoagul...