PURPOSE To analyze the deposition of amyloid and its precursors in eyes of patients with familial amyloidosis, Finnish (FAF; Meretoja's syndrome), a hereditary systemic amyloidosis. METHODS Autopsy eyes from three patients with FAF and ten control eyes were studied by Congo red staining and with antibodies to the nonmutated part of gelsolin (GS-2C4), the mutated gelsolin Asn-187 fragment (AGe...

The current mode of clinical aided diagnosis Ocular Myasthenia Gravis (OMG) is time-consuming and laborious, it lacks quantitative standards. An diagnostic system for OMG proposed to solve this problem. values calculated by the include three indicators: eyelid distance, sclera palpebra superior fatigability test time. For first two indicators, semantic segmentation method was used extract patho...

The surgical methods of treating myopia may be divided into two groups: (I) Removal of the clear lens (Fukala, I890), operations on the cornea to reduce its refractive power (Sato, Akiyama, and Shibata, I953), lamellar resection of the sclera, implantation of an intraocular lens (Choyce, I964). These operations decrease the degree of myopia but do not check its progress. (2) Operations which di...

The method of photonic band structure is used to calculate the frequencies of light that propagate in lattice models of the cornea and sclera of the mammalian eye, providing an explanation for transparency in the cornea that first properly accounts for multiple scattering of light. Each eye tissue is modeled as an ordered array of collagen rods, and photonic band structure methods are used to s...

PURPOSE The turnover of chick scleral proteoglycans from control and form-vision deprived (myopic) eyes was compared in vivo and in explant cultures to determine whether proteoglycan degradation is altered during the development of myopia and to characterize the mechanism of proteoglycan turnover in the sclera. METHODS Seven-day-old chicks were radiolabeled via an intraperitoneal injection of...

PURPOSE To investigate the effect of prostaglandins (PGs) on the permeability of human sclera in vitro. METHODS Twenty-three pairs of human eye bank eyes were studied. Circular pieces of sclera were cultured in low-serum DMEM/F-12 media. Scleral hydration was assessed by measuring wet and dry weight of scleral cultures incubated with medium for 3 days and with Hanks' buffered saline solution ...

In this paper, a modified algorithm for the detection of nasal and temporal eye corners is presented. The algorithm is a modification of the Santos and Proenka Method. In the first step, we detect the face and the eyes using classifiers based on Haarlike features. We then segment out the sclera, from the detected eye region. From the segmented sclera, we segment out an approximate eyelid contou...

Myopia in human and animals is caused by the axial elongation of the eye and is closely linked to the thinning of the sclera which supports the eye tissue. This thinning has been correlated with the overproduction of matrix metalloproteinase (MMP-2), an enzyme that degrades the collagen structure of the sclera. In this short paper, we propose a descriptive model of a regulatory network with hys...