We present experimental results and computer modeling on the optical properties of the human scleral tissue. The wavelength dependence of the refractive index of collagen fibers in the human scleral tissue was estimated on the base of Mie theory. Dispersion formula describing this dependence was derived. The results are general and can be used to describe optical properties of many other fibrou...

The literature on intra-ocular pressure dynamics is reviewed, including tonometer design and calibration, the influence of corneal-scleral mechanics, and scleral rigidity factors. Drugs that influence the outflow facility of the trabecular meshwork (TM) are discussed. Transmural pressure drop across the lamina cribosa (LC) is an important parameter, in terms of quantifying potential glaucoma da...

RATIONALE This is a retrospective study aimed to determine the efficacy of mini-scleral contact lens in protecting the cornea and improving vision in cases of facial palsy. PATIENT CONCERNS Patients with facial palsy get exposure keratitis because the cornea is dry. They feel pain, discomfort and excessive watering. If left untreated, it leads to permanent damage to the cornea and loss of goo...

AIMS To characterise lamina cribrosa and anterior scleral canal wall architecture in pressurised (IOP 10 mm Hg) and non-pressurised (IOP 0 mm Hg) normal monkey eyes. METHODS Eight normal eyes from eight monkeys were enucleated before sacrifice and the optic nerve heads (ONH) trephined and immersion fixed in glutaraldehyde (IOP 0). Nine normal eyes from nine monkeys were perfusion fixed in sit...

Increasing evidence suggests that unknown collagen remodeling mechanisms in the sclera underlie myopia development. We are proposing a novel organ culture system in combination with two-photon fluorescence imaging to quantify collagen remodeling at the tissue- and lamella-level. Tree shrew scleral shells were cultured up to 7 days in serum-free media and cellular viability was investigated unde...

AIM To review the rate of retinal detachment after macular hole surgery in patients who received vitrectomy and scleral buckle versus those who had vitrectomy alone. METHODS All patient charts and hospital records were examined for patients who underwent vitrectomy surgery for macular hole between September 1993 and June 1997. A total of 326 patients were identified and all were followed for ...