S proper scoring rules, including the Brier score and the logarithmic score, are standard metrics by which probability forecasters are assessed and compared. Researchers often find that one’s choice of strictly proper scoring rule has minimal impact on one’s conclusions, but this conclusion is typically drawn from a small set of popular rules. In the context of forecasting world events, we use ...

OBJECTIVE To evaluate the performance of 2 automated systems, Morpheus and Somnolyzer24X7, with various levels of human review/editing, in scoring polysomnographic (PSG) recordings from a clinical trial using zolpidem in a model of transient insomnia. METHODS 164 all-night PSG recordings from 82 subjects collected during 2 nights of sleep, one under placebo and one under zolpidem (10 mg) trea...

Protein-protein interactions take place in every aspect of life. The diversity of those interactions and their significant role in regulatory pathways account for the special interest in them. As shown in various diseases, protein-protein interactions can be deregulated and the cause of illness. Therefore, a better and more detailed understanding of protein-protein interactions is of great impo...

This work proposes a tentative model for the calculation of dimensionless distances between phonemes; sounds are described with binary distinctive features and distances show linear consistency in terms of such features. The model can be used as a scoring function for local and global pairwise alignment of phoneme sequences, and the distances can be used as prior probabilities for Bayesian anal...

Protein-protein docking protocols aim to predict the structures of protein-protein complexes based on the structure of individual partners. Docking protocols usually include several steps of sampling, clustering, refinement and re-scoring. The scoring step is one of the bottlenecks in the performance of many state-of-the-art protocols. The performance of scoring functions depends on the quality...

INTRODUCTION Bacterial vaginosis (BV) is one of the most prevalent infections in women of reproductive age. Amsel's criteria and Nugent scoring system are among the most commonly used diagnostic methods. Although Nugent scoring system is considered the gold standard for diagnosing BV, it is time consuming and costly, and its interpretation needs lab equipment and experts. Hence, most physicians...

The Korean translated Appraisal of Guidelines for Research and Evaluation II (Korean AGREE II) instrument was distributed into Korean medical societies in 2011. However, inter-rater disagreement issues still exist. The Korean AGREE II scoring guide was therefore developed to reduce inter-rater differences. This study examines the effects of the Korean AGREE II scoring guide to reduce inter-rate...

BACKGROUND The purpose of this study was to develop a predictive scoring system to identify intravenous immunoglobulin resistance in children with Kawasaki disease, to implement additional therapies early in the course of their illness and prevent coronary artery lesions. METHODS We performed a retrospective review of children with Kawasaki disease treated within 10 days of fever onset. To id...