SRGE J170245.3+130104 was discovered by the eROSITA telescope aboard SRG space observatory on March 13-15, 2020 during first half-year scan of its all-sky X-ray survey. The optical counterpart source photometrically identified as a distant quasar candidate at $z\approx5.5$. Follow-up spectroscopic observations, done in August/September with SCORPIO-II instrument BTA 6-m telescope, confirmed tha...

PURPOSE The single-radius design of the knee implant was introduced to improve the results of total knee arthroplasty (TKA) by reducing maximum extensor forces, and it also represents more physiologic quadriceps force pattern, which could have a positive effect on knee function after TKA. We studied mid-term results of single-radius designed cruciate retaining (CR) TKA. MATERIALS AND METHODS ...

Objective: To correlate parameters of implants with incidence of pain. Methods: 32 knees (31 patients) operated on between 2006 to 2008 in a serie of cases of TKA revision surgery were monitored for evidence of pain at the tip of the stem.In all we used uncemented stem Scorpio TS Total Knee ® Revision System (Stryker ®). Criteria assessed: pain in the leg or thigh without other causes, diameter...

We investigate in details the kinematics and morphology of the Seyfert galaxy NGC 6104 in order to identify the mechanism of gas transportation to the active galactic nucleus (AGN). Our observational data were obtained at the 6-m Special Astrophysical Observatory telescope with the MPFS integral-field spectrograph and the SCORPIO universal device in three modes: direct imaging, a scanning Fabry...

PURPOSE To evaluate the discrepancy between the anatomical axis of the distal femur of Japanese patients and the stem position of 5 types of femoral components. METHODS Lateral radiographs of 12 men and 88 women aged 31 to 83 (mean, 59) years with rheumatoid arthritis were evaluated. The discrepancy between the anatomical axis of the distal femur and the stem position of 5 types of femoral co...

Maurotoxin, a 34-amino acid toxin from Scorpio maurus scorpion venom, was examined for its ability to inhibit cloned human SK (SK1, SK2, and SK3), IK1, and Slo1 calcium-activated potassium (KCa) channels. Maurotoxin was found to produce a potent inhibition of Ca -activated Rb efflux (IC50, 1.4 nM) and inwardly rectifying potassium currents (IC50, 1 nM) in CHO cells stably expressing IK1. In con...

We have previously shown that MCa (maurocalcine), a toxin from the venom of the scorpion Maurus palmatus, binds to RyR1 (type 1 ryanodine receptor) and induces strong modifications of its gating behaviour. In the present study, we investigated the ability of MCa to bind to and modify the gating process of cardiac RyR2. By performing pull-down experiments we show that MCa interacts directly with...