OBJECTIVE To evaluate the feasibility and cost-effectiveness of screening programmes for colorectal cancer in Italy. DESIGN; We compared five types of programmes: annual faecal occult blood testing, sigmoidoscopy (every 5 years), faecal occult blood testing plus sigmoidoscopy (every 1 and 5 years), colonoscopy (every 10 years) (all in the age group 55-69 years, last examination at 70 years) and...

Optical colonoscopy is the preferred modality for the screening and prevention of colorectal cancer. Chromoendoscopy can increase lesion detection rate by highlighting tissue topography with a colored dye, but is too time-consuming to be adopted in routine colonoscopy screening. We developed a fast and dye-free technique that generates virtual chromoendoscopy images that incorporate topography ...

the demand of colonoscopy has been increasing rapidly due to the social interest for screening of colorectal cancer (CRC). This phenomenon is associated with the fact that colonoscopy is the most useful method for the detection and removal of colorectal polyps and that colonoscopic polypec-tomy significantly reduces the incidence and mortality of CRC. Although there are several screening modali...

BACKGROUND Recent studies showed that previous negative results from faecal immunochemical tests (FITs) for colorectal cancer (CRC) screening was associated with lower risk of advanced neoplasia (AN). We evaluated whether prior FIT results should be included to estimate the risk of AN in 2008-2012. METHODS A community-based screening practice recruited 5,813 asymptomatic residents aged 50 to ...

Worldwide, colorectal cancer is the third most frequent cancer occurring in both sexes. Screening programs for early detection enable detection of tumors at an earlier stage and have been shown to reduce death rate. Currently, colonoscopy is the investigation of choice for colorectal cancer screening and for investigation of patients with suspected colorectal cancer. However, colonoscopy remain...

There is clear evidence documenting the morbidity and mortality benefit of regular colonoscopy surveillance in reducing the high risk of primary and metachronous colorectal cancers associated with Lynch Syndrome (LS) (Jarvinen et al. 2000). The Australian NHMRC guidelines (2005) recommend LS patients undergo a colonoscopy every 1-2 years (NHMRC 2005). At Peter Mac yearly colonoscopy screening i...

BACKGROUND Decision aids can improve decision making processes, but the amount and type of information that they should attempt to communicate is controversial. We sought to compare, in a pilot randomized trial, two colorectal cancer (CRC) screening decision aids that differed in the number of screening options presented. METHODS Adults ages 48-75 not currently up to date with screening were ...

Introduction Increasing efforts to reform health care and contain medical expenditures have accelerated the push to define, capture, and enforce quality measures for delivered care. This trend is evident particularly for procedural and preventative measures that can have a marked effect on patient outcomes and health care costs, such as the use of colonoscopy for screening and surveillance for ...

Transl Gastroenterol Hepatol 2017;2:9 tgh.amegroups.com Post-colonoscopy colorecta l cancer or so-cal led “interval cancer” has emerged as one of new research topics, attracting much attention of endoscopists, gastroenterologists, and oncologists alike (1-4). In addition to lesions missed during the index colonoscopy due to technical issues (e.g., skills of endoscopists, quality of bowel prepar...

Screening has a central role in colorectal cancer (CRC) control. Different screening tests are effective in reducing CRC-specific mortality. Influence on cancer incidence depends on test sensitivity for pre-malignant lesions, ranging from almost no influence for guaiac-based fecal occult blood testing (gFOBT) to an estimated reduction of 66-90% for colonoscopy. Screening tests detect lesions in...