Scutellaria baicalensis has a wide range of biological activities and has been considered as an important traditional drug in Asia and North America for centuries. A partial-length cDNA clone encoding phytoene synthase (SbPSY) and full-length cDNA clonesencoding phytoene desaturase (SbPDS), ξ-carotene desaturase (SbZDS), β-ring carotene hydroxylase (SbCHXB), and zeaxanthin epoxidase (SbZEP)were...

Scutellaria is one of the largest genera in Lamiaceae with an estimated 400–500 species a nearly worldwide distribution. Most occur N hemisphere, Caucasus and wider Irano-Turanian region housing large number taxa, many them considered endemic. We present overall phylogeny monophyletic genus based on rapidly evolving plastid regions (matK-trnK, rpl16, trnL-F). Three well-supported clades are evi...

BACKGROUND Flavocoxid is a prescription medical food that is used to treat osteoarthritis. It is a proprietary blend of 2 flavonoids, baicalin and catechins, which are derived from the botanicals Scutellaria baicalensis and Acacia catechu, respectively. OBJECTIVE To describe characteristics of patients with acute liver injury suspected of being caused by flavocoxid. DESIGN Case series. SE...

objective: scutellaria luteo-caerulea bornm. & snit. is one of the species of genus scutellaria, within the family of the lamiaceae, that is used for immune system stimulation and antibacterial effects in traditional medicine in iran. the aims of this study were to analyze essential oils and mineral element contents of leaves of  s. luteo-caerulea in flowering stage of development. materials an...

Jelen tanulmány a Vértesalja homoki bükköseinek társulási viszonyait mutatja be 25 cönológiai felvétel alapján. Faji összetételére Fagetalia elemek magas aránya jellemző. Különösen értékes fajai Corydalis intermedia, Daphne laureola és Scutellaria columnae. A felvételek hagyományos sokváltozós statisztikai elemzések alapján elkülönülnek Belső-Somogy bükköseitől (Leucojo verno-Fagetum), Dunántúl...

Baicalein is a purified flavonoid extracted from the roots of Scutellaria baicalensis or Scutellaria radix. Although previous studies have suggested that Baicalein possesses an in vitro anti-hepatocellular carcinoma activity, its in vivo effects and mechanisms of action are still not completely understood. In this study, Baicalein at concentrations of 40-120 µM exhibited significant cytotoxicit...

Anthocyanin is the main pigment forming floral diversity. Several transcription factors that regulate the expression of anthocyanin biosynthetic genes belong to the R2R3-MYB family. Here we examined the transcriptomes of inflorescence buds of Scutellaria species (skullcaps), identified the expression R2R3-MYBs, and detected the genetic signatures of positive selection for adaptive divergence ac...

Angiogenesis, which plays a critical role during tumor development, is tightly regulated by the Sonic Hedgehog (SHH) pathway, which has been known to malfunction in many types of cancer. Therefore, inhibition of angiogenesis via modulation of the SHH signaling pathway has become very attractive for cancer chemotherapy. Scutellaria barbata D. Don (SB) has long been used in China to treat various...

BACKGROUND Flavonoid-rich extracts from the mature roots of Scutellaria baicalensis have been shown to exhibit antiproliferative effects on various cancer cell lines. We assessed the ability of an ethanolic extract of S. baicalensis root to inhibit the proliferation of malignant glioma cells. METHODS Cell lines derived from primary and recurrent brain tumors from the same patient and cells se...