In this paper we study post-penalized estimators which apply ordinary, unpenal-ized linear regression to the model selected by first-step penalized estimators, typically LASSO.

The present study examines the achievement goals of university instructors, particularly the structure of such goals, and their relationship to biographic characteristics, other aspects of instructors' motivation, and teaching quality. Two hundred and fifty-one university instructors (184 without Ph.D., 97 with Ph.D., thereof 51 full professors; 146 males, 92 females) answered a questionnaire m...

A survey is given of differential expression analyses using the linear modeling features of the limma package. The chapter starts with the simplest replicated designs and progresses through experiments with two or more groups, direct designs, factorial designs and time course experiments. Experiments with technical as well as biological replication are considered. Empirical Bayes test statistic...

Familial cutaneous collagenoma is an inherited connective tissue nevus, which presents with asymptomatic symmetrically distributed skin nodules on the trunk or upper limbs. Here, we describe a case of a 12-year-old girl with collagenoma affecting the lower back.

In this report, we examine several morphologic aspects of blue nevi of internal organs, and compare them to similar conditions of the skin. From a morphologic point of view, blue nevi of internal organs are more similar to the so-called dermal melanocytoses. Nevertheless, since melanocytoses and blue-nevi seem to have the same benign prognosis, and since blue nevus is a historically consolidate...