Covering: 2012 to 2016Metabolic engineering using systems biology tools is increasingly applied to overproduce secondary metabolites for their potential industrial production. In this Highlight, recent relevant metabolic engineering studies are analyzed with emphasis on host selection and engineering approaches for the optimal production of various prokaryotic secondary metabolites: native vers...

Lichens produce a plethora of primary and secondary metabolites. Secondary metabolites have several biological functions that can be used for human health. Recent studies described their antioxidant, anti-inflammatory, antimycotic, antibiotic/antiviral activities. However, attention has mainly been focused on antiproliferative, cytotoxic, anticancer effects. Because there are many publications ...

as an aromatic and colorful plant of substantive taste, saffron (crocus sativus l.) owes such properties of matter to growing class of the secondary metabolites derived from the carotenoids, apocarotenoids. regarding the critical role of micrornas in secondary metabolic synthesis and the limited number of identified mirnas in c. sativus, on the other hand, one may see the point how the characte...

The number of known so-called “secondary metabolites” (also referred to as “natural products”) that have been discovered to date is increasing at a constant rate. Yet, it is not only plants (as described in this book) that produce these bioactive compounds; rather, other organisms such as bacteria, fungi, sponges, as well as animals, are also capable of synthesizing a plethora of these metaboli...

salicylic acid (sa) and methyl jasmonate (meja) as phytohormone regulate synthesis of secondary metabolites in a wide range of plant species thereby accumulation of phenylalanine ammonia lyase enzyme (pal) and accelerate of oxygen free radicals, protein kinas and no production. the present research designed to evaluate effect of sa and meja elicitation on accumulation of phenolic compounds, fla...

Secondary plant metabolites reveal numerous biological activities making them attractive as resource for drug development of human diseases. As the majority of cancer drugs clinically established during the past half century is derived from nature, cancer researchers worldwide try to identify novel natural products as lead compounds for cancer therapy. Natural products are considered as promisi...

From the fresh leaves or twigs of Aptenia cordifolia, a total of 29 compounds were isolated, including the new tetranoroxyneolignan 18, the new dilignan 19, and the beta-ionone derivative 27, previously only known as a synthetic compound, together with 26 known compounds. The structures of the new products were determined by (1)H-, (13)C-, and 2D-NMR, as well as HR-MS analyses. The phytotoxic e...

Increasing awareness of hazards associated with the use of antibiotic and chemical feed additives has accelerated investigations into plants and their extracts as feed additives. The present review mainly discusses two classes of plant secondary compounds in this context, i.e. essential oils and saponins. The broader potential of plants and their extracts is illustrated by the progress of an EC...

Column chromatography of the light petroleum fraction from the methanolic extract of the stem bark of Salix tetrasperma Roxb. (Salicaceae) resulted in the isolation of beta-sitosterol acetate, friedelin, 3beta-friedelinol, beta-amyrin, beta-sitosterol, beta-sitosterol-O-glucoside in addition to palmitic acid. From the dichloromethane fraction of the leaves, catechol and tremulacin were isolated...