AIM Patient's perception of seizure precipitant is crucial in epilepsy management, but it is often overlooked by physicians. This may be due to neglect and underestimation of its importance. This study looked at frequency and nature of self-perceived seizure precipitants among patients with epilepsy. MATERIALS AND METHODS A close-ended questionnaire-based study. Patients with active epilepsy ...

introduction: olive leaf contains anti-inflammatory and cox-2 inhibitor compounds. considering the role of the cox enzyme in seizures, this research was performed to assess the effects of this extract in treatment of seizures induced by ptz. methods: in this research, male wistar rats (200±20 g) were injected intra-cerebroventricularly with 1 μl saline or olive leaf extract (125 μg, 250 μg and ...

ObjectivesTo investigate the clinical characteristics, final diagnosis, investigation results, management, response to anti-seizure medications (ASMs) and outcomes of individuals assessed in a First Seizure service over 5-year period.MethodsRetrospective analysis 772 who were clinically dedicated at National Hospital for Neurology & Neurosurgery (NHNN), Queen Square period.Results772 following ...

In a given population, certain individuals are much more likely to have seizures than others. This increase in seizure susceptibility can lead to spontaneous seizures, such as seen in idiopathic epilepsy, or to symptomatic seizures that occur after insults to the nervous system. Despite the frequency of these seizure disorders in the human population, the genetic and physiological basis for the...

Although much is known about persistent molecular, cellular, and circuit changes associated with temporal lobe epilepsy, mechanisms of seizure onset remain unclear. The dentate gyrus displays many persistent epilepsy-related abnormalities and is in the mesial temporal lobe where seizures initiate in patients. However, little is known about seizure-related activity of individual neurons in the d...

A retrospective review of children with epilepsy and obstructive sleep apnea, treated surgically for their obstructive sleep apnea from January 2008-October 2010, was performed for age, sex, type of epilepsy, antiseizure medications, sleep-study data, and changes in seizure frequency. Twenty-seven subjects (median age, 5 years) with no adjustment to their medications around their time of surger...

OBJECTIVE This study examined the effect of stimulus parameters on the occurrence of adequate seizures and reconsidered the factors related to motor seizure duration. METHODS The medical records of 187 patients who received ECT in Asan Medical Center from January 2007 to May 2014 were retrospectively reviewed. The starting stimulus dose was determined using a preselected-dose method and the c...