OBJECTIVE To evaluate seminal plasma coenzyme Q10 (CoQ10) levels and oxidative stress in patients with different types of male infertility. METHODS A case-control study was carried out in the Department of Chemistry and Biochemistry, College of Medicine, Al-Nahrain University, Baghdad, Iraq from the period of November 2004 to July 2006. Sixty patients with male infertility were recruited from...

The cervix is central to the female genital tract immune response to pathogens and foreign male Ags introduced at coitus. Seminal fluid profoundly influences cervical immune function, inducing proinflammatory cytokine synthesis and leukocyte recruitment. In this study, human Ect1 cervical epithelial cells and primary cervical cells were used to investigate agents in human seminal plasma that in...

Seminal plasma is comprised of the extracellular sperm milieu from spermatogenesis in the testes, through to maturation in the epididymis, as well as secretions from the accessory sex glands. Consisting primarily of proteins, this substance has a multitude of functions in mammalian reproduction. Seminal plasma influences sperm physiology, success of semen freezing, migration of spermatozoa thro...

Background Leptin, as a key hormone in energy homeostasis, plays an important role in reproduction and male fertility. However, its negative or positive effect on sperm quality and assisted reproduction technique is still controversial. The aim of this study was the comparison of seminal leptin concentration in selected couples with male and female factor for intracytoplasmic microinjection (IC...

Rabbit spermatozoa from the epididymis lack the antigenic material present on seminal spermatozoa, which these latter cells have in common with the seminal plasma. This observation provides further support for the indirect evidence, obtained previously, that antigenic material is taken up by the spermatozoa from the seminal plasma.

BACKGROUND Many factors may lead to sperm DNA damage. However, it is little known that the correlations of sperm DNA damage with obesity-associated markers, and reproductive hormones and lipids levels in serum and seminal plasma. METHODS In our prospective study, a total of 1 010 subfertile men, aged from 18 to 50 years old, were enrolled from August 2012 through June 2015. Their obesity-asso...

Semen hyperviscosity (SHV) is one of the factors involved in deficiency in sperm function. This research aimed to evaluate seminal plasma total antioxidant capacity (TAC) and malondialdehyde (MDA) levels in infertile patients with hyperviscous and non-hyperviscous semen samples to understand whether hyperviscous semen is associated with oxidative damage in infertile subjects. In this cross sect...

Background: Seminal plasma of mammals is a complex fluid, which serves as a carrier for the spermatozoa on their journey from the male testes to their target, the oocyte. Seminal plasma contains a variety of biochemical components, some of which are relatively specific for the regulation of sperm function. The objective of this study was to investigate enzyme activities aspartate-amino-transfer...

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