BACKGROUND Sentinel lymph node biopsy is a recently developed, minimally invasive technique for staging the axilla in patients with breast cancer. It has been suggested that this technique will avoid the morbidity associated with more extensive axillary dissection. A wide range of different methods and materials has been employed for lymphatic mapping, but there has been little consensus on the...

AIM To investigate the applicability of the sentinel lymph node biopsy technique in early stages of endometrial cancer. MATERIAL AND METHODS A prospective study that included consecutive patients with a histological diagnosis of clinical state I endometrial carcinoma was performed. Two doses of 2 mCi (74 MBq) of (99m)Tc-albumin nanocolloid were injected in the uterine cervix, and planar and S...

AIM The sentinel lymph node biopsy (SLNB) was firstly introduced by Giuliano and co. in 1994 for the treatment of breast cancer; in comparison to the axillary lymph node dissection (ALND), the sentinel lymph node biopsy has shown both a lower morbidity and acceptable distance results. We want to show that this technique is reliable and should be used routinely in selected cases. MATERIALS OF ...

Malignant melanoma is the world's fastest growing cancer, in terms of incidence, in the Caucasian population. There is a paucity of data regarding age-related population based studies in Chinese people. There are observations to suggest that malignant melanoma is a different disease in the Chinese with a far higher proportion of lesions being acral lentiginous in nature. Controversy abounds reg...

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PURPOSE sentinel lymph node biopsy in early-stage breast cancer patients has been substituting the total axillary lymph node is presented dissection. The technique of processing the sentinel lymph node and the aim of this study was to investigate the efficacy of occult metastasis identification based on the standard histological and immunohistochemical examination. METHODS between 2002 and 20...

Lymphatic mapping and sentinel node biopsy were initially developed for nodal staging in the malignant melanoma population. Morton and colleagues developed a procedure that permits intraoperative identification of the sentinel lymph node, the first node in the lymphatic basin from which the primary tumor drains. If that sentinel node is negative for metastatic disease, the remaining nodes in th...