Single doses of norfloxacin (200, 400, 800, 1,200, and 1,600 mg) or placebo were administered orally at weekly intervals to 14 healthy male volunteers in a double-blind study. Norfloxacin was measured in serum and urine by high-pressure liquid chromatography with UV detection. The concentrations of this drug in serum peaked 1 to 2 h after each dose; the mean peak values for increasing doses wer...

An application of the Generalized Minimal Residual (GMRES) algorithm to the solution of sequentially multiple nearby systems of equations through the reuse of Krylov subspaces is presented. The main focus is on the case when only the right-hand side vector changes. However, the case in which both the matrix and the right-hand side change is also addressed. Applications of these formulations inc...

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Much of current data mining research is focused on discovering sets of attributes that discriminate data entities into classes, such as shopping trends for a particular demographic group. In contrast, we are working to develop data mining techniques to discover patterns consisting of complex relationships between entities. Our research is particularly applicable to domains in which the data is ...

3 New meshfree method employing the Node-based Smoothed Point Interpolation Method 4 (NS-PIM) is presented as an alternative to the non-linear finite element approach for concrete 5 members. The non-linear analysis is replaced by sequentially linear analyses (SLA), and 6 smeared, fixed concrete cracking model was used. A notched concrete beam was employed 7 for validation. Using a crack band wi...

It is well known that for the case of a countable partial order, the ideal completion and the chain completion coincide. We investigate the boundary at which the chain and ideal completion do not coincide. We show in particular that the ideal completion is not sequentially adequate; that is it is not possible in general to simply replace the ideal completion with a completion based on sequences...

(i) CAC iff every countable product of sequential metric spaces (sequentially closed subsets are closed) is a sequential metric space iff every complete metric space is Cantor complete. (ii) Every infinite subset X of R has a countably infinite subset iff every infinite sequentially closed subset of R includes an infinite closed subset. (iii) The statement “R is sequential” is equivalent to eac...