OBJECTIVES Severe congenital diarrhea occurs in approximately half of patients with Aristaless-Related Homeobox (ARX) null mutations. The cause of this diarrhea is unknown. In a mouse model of intestinal Arx deficiency, the prevalence of a subset of enteroendocrine cells is altered, leading to diarrhea. Because polyalanine expansions within the ARX protein are the most common mutations found in...

Rhetoric about spirituality and the human search for spiritual answers has been part of history for many years, and spiritual care has been part of nursing history since ancient times (Narayanasamy 1999c). Humans have a profound need to understand their spirits (Freeman 1998), which is the core of human existence and the most elusive and mysterious constituent of our human nature (Macquarrie 19...

In this paper it is studied that there are statistically relevant differences in the brain activity intensity between subjects with an alleged higher development of Spatial Intelligence and those subjects without this alleged higher development. We will analyze their performance on a Spatial Intelligence task of identification, attention and recognition of virtual tridimensional geometric patte...

Humans have a strong sense of who should be punished, when, and how. Many features of these intuitions are consistent with a simple adaptive model: Punishment evolved as a mechanism to teach social partners how to behave in future interactions. Yet, it is clear that punishment as practiced in modern contexts transcends any biologically evolved mechanism; it also depends on cultural institutions...

Three studies explored how the traits that people ideally desire in a romantic partner, or ideal partner preferences, intersect with the process of romantic relationship initiation and maintenance. Two attraction experiments in the laboratory found that, when participants evaluated a potential romantic partner’s written profile, they expressed more romantic interest in a partner whose traits we...

A motivation behind much UbiComp research has been to make our lives convenient, comfortable and informed, following in the footsteps of Weiser’s calm computing vision. Three themes that have dominated are context awareness, ambient intelligence and monitoring/tracking. While these avenues of research have been fruitful their accomplishments do not match up to anything like Weiser’s world. This...

The role of biology in psychology changes from animals to humans. Biology determines animal behaviour in natural environments. For humans the biological forces changes to an energizing function. They recede in the background and the higher psychological functions govern consciousness and behavior. Humans do not have to obey the instincts or reflexes, but have the option to do what they decide t...

Preliminary Sermon: Humans will be Humans; The Medium is the Message The famous Catalan numbers (see [Sl1]), count zillions of combinatorial families (see [St]) and many humans have fun trying to find ‘nice’ bijections between family A and family B. While this may be fun for a while, sooner or later this game gets old, especially since the real reason Catalan numbers are so ubiquitous is their ...

In this paper we present the first experimental step of a larger study investigating the effects of agents’ gender identification on the perceived interaction quality. The purpose was to determine how test subjects judge the ‘gender’ of virtual humans. 48 test subjects rated 7 agents according to their degree of feminity, masculinity and gender ambiguity. The results showed that subjects’ gende...

Thioredoxins are proteins that participate in different cellular processes via redox-mediated reactions. For humans, we have recently described two novel members of this family that display a male germ cell specific expression pattern, named spermatid specific thioredoxin (Sptrx-1 and Sptrx-2 respectively). We report here the cloning and characterization of the mouse Sptrx-1 gene and protein, w...