The present study was undertaken to study the free radical activity in malaria patients suffering from plasmodium falciparum (n=14) and plasmodium vivax (n=21) against the healthy control subjects (n=25). Lipid peroxidation was assessed by measuring serum lipid peroxide in both groups of malaria patients by using Malondialdehyde as standard. The serum Ceruloplasmin is also studied along with se...

BACKGROUND Saliva in dogs, as in humans, is a complex fluid secreted by different salivary glands in the oral cavity to protect the oral mucosa and teeth. The use of saliva as a substitute for blood in diagnosing and prognosticating disease in humans is widely accepted. Salivary biochemistry has also been used as a marker for periodontal disease in humans. No studies have as yet investigated th...

BACKGROUND Soshiho-tang (SST, Xiao-chai-hu-tang in Chinese and Sho-saiko-to in Japanese), an oriental herbal formula, is used for treatment of chronic liver diseases. Although many researchers have studied the pharmacological properties of SST, information about its safety and toxicity is limited. Therefore, we evaluated the potential safety of SST in Sprague-Dawley rats over a period of 4-week...

2-(l-Menthoxy)ethanol has been frequently employed as a flavoring agent; however, data regarding 2-(l-menthoxy)ethanol toxicity remain limited. We performed 13-week subchronic study of in male and female F344 rats, with doses 0, 15, 60, or 250 mg/kg body weight (BW)/day orally administered by gavage using corn oil the vehicle. No significant toxicological changes general condition, weight, food...

BackgroundThe nuclear receptor farnesoid X (FXR) is a key regulator of hepatic BA and lipid metabolism, inflammation fibrosis. Here, we aimed to explore the potential cilofexor, non-steroidal FXR agonist, as therapeutic approach for counteracting features cholestatic liver injury by evaluating efficacy mechanisms in Mdr2/Abcb4 knockout (-/-) mouse model sclerosing cholangitis.MethodsFVB/N WT Md...

This study aimed to clarify the relationship between serum 25-hydroxyvitamin D concentration body composition by examining male university rugby players in a cross-sectional manner. The subjects were 36 (mean age: 20.2 years) who provided us with data regarding their composition, blood biochemistry examination, and dietary intake frequency. Examination of concentrations 【25 (OH) D】 showed that ...

Aim: To find out association of Serum Thyroid Stimulating Hormone (TSH) and Anti-Thyroid Antibodies (ATA) i.e., anti Tg-Ab & TPO-Ab with thyroid carcinoma in nodule patients presented Mayo Hospital Lahore. Study design: It was a comparative cross-sectional study. Methods: wasconducted Biochemistry Department Biomedical Sciences KEMU, Lahore from February 2018 to May 2019. Seventy were inclu...

Background: Serum creatinine is the most requested parameter in current practice context of functional exploration kidney. Its contribution to medical care particularly decisive for kidney transplant patients. The aim study compare colorimetric and enzymatic techniques available our laboratory determination samples from patients.
 Methods: Prospective carried out at Biochemistry University...

A 42 days experiment was carried out to evaluate the effects of dried Centella asiatica leaf meal (CSP) as an herbal feed additive on the growth performance, haematology and serum biochemistry of broiler chicken. A total of 200 Ross 308 day old broiler chicks of mixed sex was divided into four (4) treatment groups of fifty (50) birds, each group was further divided into five replicates each of ...