The rate at which displacement and recovery of the acid-base equilibrium of the blood occur in young adult males subjected to short periods of maximal exertion has been determined. Displacement of acid-base equilibrium produced by severe exercise is along the fixed acid path, similar to the path of displacement produced by ingestion of acidifying agents such as ammonium chloride. Maximum displa...

The compounds, 2-(methylsulfonyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid (DM3), 2-(phenylsulfonyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid (DM(4)), and 2-(p-toluenesulfonyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid (DM(5)) were synthesized by coupling of 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid (DM(2)) with methanesu...

The effects of chloride on dissolution and toxicity of silver nanoparticles (AgNPs) have been well studied. However, their intermediate shapes during the transition have not been illustrated to-date. Herein, the chloride-induced shape transformation process of AgNPs under long-term, low-concentration conditions is explored. A unique triangular Ag-AgCl heterostructure is observed. The structure ...

UNLABELLED Animal studies have shown that large volumes of IV lactated Ringer's solution (LR) decrease serum osmolality, thereby increasing cerebral water. These studies have led to recommendations to limit LR to avoid cerebral edema in neurosurgical patients. Eighteen healthy human volunteers aged 20-48 yr received 50 mL/kg LR over 1 h on one occasion and 0.9% sodium chloride (NS) on another. ...

1. A procedure for the rapid, accurate estimation of haptoglobin in serum and purified preparations is described, based on the peroxidase activity of haemoglobin in its complexes with haptoglobin. 2. Hydrogen peroxide, guaiacol and methaemoglobin reagents are used, under well-defined conditions which reduce the peroxidase activity of free haemoglobin essentially to zero. The reaction is followe...

Direct read-out of chloride concentration is provided by an auxiliary designed for use with the automatic coulometric-amperometric titrator of Cotiove et al. (1). The circuitry, construction, and operation of the auxiliary are described. Automatic titration of samples of biologic fluids such as serum, cerebrospinal fluid, urine, sweat, and gastrointestinal fluids requires no prior preparation a...

Significant increase in ovarian and uterine weight and stimulation of ovarian delta5-3beta-hydroxysteroid dehydrogenase (delta5-3beta-HSD) activity and elevation of serum estradiol level were observed following gold chloride (0.2 mg/kg body weight/day), s.c. administration in immature female albino rats. Moreover, normal cyclic changes of estrus were found in vaginal smears of these rats wherea...

Because of the inherent sensitivity of the dropping mercury electrode when used for the quantitative analysis of inorganic ions, the present study was undertaken to determine whether sufficient accuracy and simplicity of operation could be attained to justify its employment as a micromethod for the determination of chloride in blood. Since it was desired to work with such samples as can be conv...

Background: Sickle cell anaemia, a type of haemoglobinopathy is associated with biochemical abnormalities such as imbalance of electrolytes. Aim: To determine and evaluate saliva as a biochemical indicator for electrolyte estimation in sickle cell anaemic patients. Materials and methods: 30 children in the age group of 4-12 years were split into two equal groups: sickle cell anaemia group and c...

We studied dynamic processes in drying drops of model protein-salt solutions, using an uncoated quartz resonator as a biosensor. To measure these processes we developed a method based on recording the dynamics of the Acoustic-Mechanical Impedance (AMI) of a drop as it dried on the surface of a quartz resonator oscillating at a resonant frequency of 60 kHz. The aim of this work was to highlight ...