Increases in serum and liver copper content are noted during iron deficiency in mammals, suggesting that copper-dependent processes participate during iron deprivation. One point of intersection between the 2 metals is the liver-derived, multicopper ferroxidase ceruloplasmin (Cp) that is important for iron release from certain tissues. The current study sought to explore Cp expression and activ...

Trace elements are extremely important for normal metabolism. Copper is one of the trace metals which has important physiological function in maintaining thyroid activity. Copper is known to effect lipid metabolism. Increase in serum copper level is associated with decrease in concentration of total cholesterol (TC). Thyroid hormone binding transcription factors, which are essential for modulat...

Ceruloplasmin (Cp) concentration and oxidative activity in serum are lowered in Parkinson's disease (PD). In most PD patients, iron increases in the substantia nigra in the midbrain. In PD, the low Cp concentration and activity in serum and the high iron amounts in the substantia nigra appears to be correlated. An hereditary background is common in PD and variations in the Cp gene that have bee...

Adverse outcomes of pregnancy increase among women with high density of hemoglobin. This study evaluates the effects of iron supplementation on serum copper level in pregnant women with hemoglobin higher than 13.2 g/dl. Sixty two pregnant women with Hemoglobin >13.2 g/dl and normal serum copper levels in their 13-18 weeks of gestation were randomized into case and control groups. From 20 week t...

BACKGROUND Copper is essential as a trace element for metabolic processes. Exposure to copper in industries develops toxicity among the workers. Previous findings on adverse effects of copper on male reproductive function in adult albino rats led to investigate the effects of this metal on reproductive function of maturing male rats in the present experiment. METHODOLOGY To study these effect...

In order to evaluate the status of zinc and copper in pregnant women and in preeclampsia, we conducted a prospective case-control study. It involved 56 pregnant women compared with 30 non-pregnant women selected as controls. For pregnant women, serum levels of zinc, copper and ceruloplasmin were determined quarterly. These same measurements were performed once in controls. The comparison of var...

INTRODUCTION Aim of this study was the training effect evaluation on the Special Aviation Gymnastics Instruments (SAGI) on blood metallothionein (MT), zinc (Zn), copper (Cu), protein, neuron-specific enolase (NSE), and physical fitness in the examined cadets. MATERIAL AND METHODS The study comprised 55 cadets, aged 20, divided into two groups: examined group A (N=41) and control group B (N=14...

I. The strength of binding of 64CU to the following was determined by dialysis against solutions of buffered sodium chloride with and without EDTA, penicillamine and sodium glycocholate. (a) Human albumin, serum and bile labelled in vitro from patients with and without Wilson's disease. (b) Rat bile labelled in vivo and in vitro. 2. Serum and albumin were found to bind copper comparatively weak...

BACKGROUND It is well known that some trace elements such as zinc and copper play a significant role in many forms of hair loss. However, the effect of zinc and copper in the pathogenesis of hair loss is still unknown. OBJECTIVE The purpose of this study is to evaluate the zinc and copper status in each of four types of hair loss. METHODS A study was carried out with 30 health controls and ...