Epilepsy is a neurological disease that requires long-term drug therapy. Carbamazepine (CBZ) effective in partial seizures, including complex and tonic-clonic seizures. It was aimed to evaluate the effect on serum lipid profile patients who used CBZ. Medical biochemistry laboratory data between January December 2021 were analyzed retrospectively. Patients (n=59) monotherapy at least 2 years of ...

Aim of the study was to investigate role C-reactive protein as an indicator multimorbidity in patients with arterial hypertension. Material and methods. A retrospective archival data 1958 hypertension who were examined treated at clinic Federal Research Center for Fundamental Translational Medicine (Novosibirsk) carried out. 2 groups allocated depending on concentration blood serum: normal elev...

BACKGROUND/AIM Our previous studies showed that administration of dexamethasone plus food increased serum leptin levels 100% more than dexamethasone alone. We hypothesized that this increase in leptin from the meal could result directly from the provision of fuel metabolites rather than from the meal-induced rise in insulin. In the current study, we tested the effect of an i.v. lipid fuel sourc...

the present study investigated the effects of e. coli lipopolysaccharide (lps) induced mastitis model in rat on the activity of antioxidant enzyme systems. to achieve this purpose, e. coli lps were infused into the mammary gland of 12 rats 72 hr postpartum and compared with 12 rats in control group infused intramammary placebo sterile pyrogene – free, physiological saline. the antioxidant activ...

The lipid A component of bacterial lipopolysaccharides (endotoxins), when complexed to bovine serum albumin (BSA) or human serum albumin (HSA), was shown to be a potent pyrogen. Furthermore, rabbits could be protected against endotoxin fever by immunization with both lipid A BSA and lipid A HSA complexes. The results presented in this paper show that lipid A is responsible for the pyrogenic act...

The lipid A component of bacterial lipopolysaccharides (endotoxins), when complexed to bovine serum albumin (BSA) or human serum albumin (HSA), was shown to be a potent pyrogen. Furthermore, rabbits could be protected against endotoxin fever by immunization with both lipid A.BSA and lipid A.HSA complexes. The results presented in this paper show that lipid A is responsible for the pyrogenic act...

metronidazole, a synthetic derivative of the nitroimidazole class is a known antibacterial and antiprotozoal agent. the hypolipidemic effect of metronidazole was not known. the authors noticed it incidentally for the first time. after quazi experimental studies on several cases, it was revealed that 750 mg of metronidazole for 10 days significantly decreased serum cholesterol. this trial was pe...