Premature return to play (RTP) following sports-related concussion (SRC) is associated with significant morbidity including risk of neurological and non-neurological injury, persistent post-concussion symptoms chronic deficits. Assessing athletes for RTP critical but these decisions are currently based on clinical assessments that subject bias symptomatic reporting rely compliance. An objective...

Sodium disorders are the most common and most poorly understood electrolyte disorders in neurological patients. The aim of this study was to determine the incidence of sodium disorders and its association with different traumatic brain injuries. This prospective study was conducted in 80 patients diagnosed with moderate and severe traumatic brain injuries. All patients underwent cerebral comput...

c Abstract: Background: Traumatic Brain Injuries (TBIs) are a leading cause of morbidity, mortality, disability and socioeconomic losses in India and other developing countries. The first Computed Tomography (CT) scan of TBI patient is vital in diagnosing underlying neuroparenchymal injury and also plays a predictive role. Aim and Objectives: We intended to correlate features on the admission C...

Allison C. Bain and David F. Meaney Department of Bioengineering University of Pennsylvania An in vivo, tissue-level, mechanical threshold for functional injury to CNS white matter was determined by comparing electrophysiological impairment to estimated tissue strain in an in vivo model of axonal injury. Axonal injury was produced by transiently stretching the right optic nerve of an adult male...

Diffuse axonal injury (DAI), a type of traumatic injury, is known for its severe consequences. However, there are few studies describing the outcomes of DAI and the risk factors associated with it. This study aimed to describe the outcome for patients with a primary diagnosis of DAI 6 months after trauma and to identify sociodemographic and clinical factors associated with mortality and depende...

INTRODUCTION Blast injury to brain, a hundred-year old problem with poorly characterized neuropathology, has resurfaced as health concern in recent deployments in Iraq and Afghanistan. To characterize the neuropathology of blast injury, we examined the brains of veterans for the presence of amyloid precursor protein (APP)-positive axonal swellings typical of diffuse axonal injury (DAI) and comp...