OBJECTIVE Sex steroid hormones are thought to contribute to the growth, differentiation, and progression of prostate cancer. We investigated plasma levels of sex steroid hormones and length of the androgen receptor gene CAG repeat in relation to incident prostate cancer diagnosed in the prostate-specific antigen (PSA) era. METHODS Using a nested case-control design, we included 460 prostate c...

Sexual fate is no longer seen as an irreversible deterministic switch set during early embryonic development but ongoing battle for primacy between male and female developmental trajectories. That sexual not final must be actively maintained via continuous suppression of the opposing network creates potential flexibility into adulthood. In many Animals, sexuality only extremely plastic, sex cha...