OBJECTIVES We sought to investigate the effects of physical training on circulating proinflammatory cytokines and the soluble apoptosis mediators Fas (sFas) and Fas ligand (sFasL) in patients with chronic heart failure (CHF). BACKGROUND Recent investigations have shown an overexpression of circulating proinflammatory cytokines and soluble apoptosis mediators in patients with CHF, which may be...

Reef-building corals present various colony morphologies that may greatly influence their nutritional ecology. Fatty acids (FAs) and lipids are important components of have been increasingly used to research the ecology corals. In this study, we examined symbiodiniaceae density, corallite area, total lipid content, FAs composition 14 species with different morphologies. The results showed morph...

From the Magle Stora Kyrkogata 9, Lund, Sweden (U.R.); Saint Luke’s Mid America Heart Institute, Kansas City, MO (J.J.D.); Faculty of Science and Technology, Institute of Clinical Exercise and Health Science, University of the West of Scotland, Hamilton, Lanarkshire, United Kingdom (Z.H.); Department of Comparative Biosciences, University of Illinois at Urbana-Champaign, Urbana (F.A.K.); Instit...

PURPOSE To compare soluble Fas, FasL and Bcl-2 in Graves' disease (GD) and Hashimoto's thyroiditis (HT) to the markers of humoral response: aTPO, aTG and aTSHR. MATERIAL AND METHODS 5 groups of subjects: 1) 14 patients with GD in euthyreosis on methimazol (euGD); 2) 20 patients with hyperthyroid GD (hrGD); 3) 15 patients with HT in euthyreosis on levothyroxine (euHT); 4) 16 patients with hypo...

Migrant and experimental animal studies suggest that differences in breast cancer incidence rates may be related, in part, to intake of dietary fat. The experimental evidence indicates that total fat, saturated, and n-6 polyunsaturated fatty acids (PUFAs) may stimulate both mammary tumor growth and metastasis, whereas n-3 PUFAs may have a tumor-inhibiting effect. Overall, epidemiological studie...

BACKGROUND The Fas receptor/ligand system including soluble forms is the most important apoptotic initiator in the liver. Dysregulation of this pathway may contribute to abnormal cell proliferation and cell death and is regarded as one of the mechanisms preventing the immune system from rejecting the tumor cells. OBJECTIVES To analyze the role of Fas system Fas/ Fas ligand (Fas/ FasL) in the ...

BACKGROUND Intrauterine fetal development is characterized by increased rates of proliferation and apoptosis, while both these processes may be attenuated post-natally. AIM Tissue polypeptide specific antigen and sFas serum concentrations were determined during pregnancy and post-natally, in order to evaluate their alterations during these crucial periods. MATERIALS AND METHODS Forty-seven ...

The optimal diet composition to prevent obesity and its complications is unknown. Study aims were to determine the association of diet composition with energy intake, homeostatic model assessment-insulin resistance (HOMA-IR), and C-reactive protein (CRP). Data were from the NHANES for eligible adults aged 20-74 y from 2005 to 2006 (n = 3073). Energy intake and diet composition were obtained by ...

OBJECTIVE To investigate the association between genetic variation in the adipocyte protein perilipin (PLIN) and insulin resistance in an Asian population as well as to examine their modulation by macronutrient intake. RESEARCH DESIGN AND METHODS A nationally representative sample (Chinese, Malays, and Indians) was selected in the Singapore National Health Survey following the World Health Or...

BACKGROUND Free fatty acids (FFAs) acutely stimulate insulin secretion from pancreatic islets. Conflicting results have been presented regarding this effect at non-stimulatory glucose concentration, however. The aim of our study was to investigate how long-chain FFAs affect insulin secretion from isolated human pancreatic islets in the presence of physiologically fasting glucose concentrations ...