Forkhead box M1 (FOXM1) and urokinase-type plasminogen activator (uPA) are overexpressed and associated with the pathogenesis of multiple types of human malignancy. The aims of the present study were to investigate FOXM1 and uPA expression levels in human gastric cancer using tissue microarray techniques; determining their association with clinicopathological characteristics as well as their pr...

We have previously demonstrated that pharmacological concentrations of 17j-oestradiol (E2) increase the cytotoxicity of methotrexate towards hormone responsive MCF-7 human breast cancer cells (Clarke et al., 1985), and this compares with the ability of E2 to potentiate the cytotoxic effects of cytosine arabinoside in these cells (Weichselbaum et al., 1978). However, E2 reduces both the antimeta...

BACKGROUND AND PURPOSE The validity of hospital discharge diagnoses is essential in improving stroke surveillance and estimating healthcare costs of stroke. The aim of this study was to assess sensitivity, positive predictive value, and accuracy of discharge diagnoses compared with a stroke register. METHODS A record linkage was made between a population-based stroke register and the discharg...

Patients’ awareness of herpes zoster (HZ) is crucial in timely treatment and preventing spreading varicella virus (VZV). We evaluate patient’s perceived severity HZ newly diagnosed patients. Polymerase chain reaction confirmed VZV positive patients ≥60 years were recruited from Kaiser Permanente Southern California 2012-5. Patients with a previous vaccine vaccination record defined as vaccinate...

Abstract Introduction It believed that those who treat sexual medicine conditions enjoy an active robust and dynamic life with their partners. The perception is medical professionals male female problems are more sexually maybe experimental in behavior. perceived they may have a willingness to discuss related topics public forums unrelated work. Objective A random sample survey was conducted as...

Background and aims—Laser induced fluorescence (LIF) from colonic mucosa was measured in vivo with and without ä aminolevulinic acid (ALA) in an attempt to diVerentiate between neoplasia and non-neoplasia in real time during colonoscopy. Methods—Spectra from 32 adenomas, 68 normal sites, and 14 hyperplastic polyps in 41 patients were obtained with a point monitoring system. Twenty one of the pa...

Percutaneous muscle biopsy is an important and acceptable technique in the study of conditions involving human skeletal muscle. A review of 436 conchotome and needle muscle biopsies obtained over 18 months in this centre is presented.