Lung cancer development in nonsmokers, particularly in females, has long been observed,but the genetic pathways of oncogenesis are still unclear. The purpose of this study was to identify important targets of chromosomal alteration involved in non-tobacco-related adenocarcinomas of lung. In this study, loci of recurrent allelic imbalance (AI) were identified by microsatellite analysis, focusing...

This review summarizes the chromosomal changes detected by molecular cytogenetic approaches in esophageal squamous cell carcinoma (ESCC), the ninth most common malignancy in the world. Whole genome analyses of ESCC cell lines and tumors indicated that the most frequent genomic gains occurred at 1, 2q, 3q, 5p, 6p, 7, 8q, 9q, 11q, 12p, 14q, 15q, 16, 17, 18p, 19q, 20q, 22q and X, with focal amplif...

spinal muscular atrophy (sma) is a genetic disorder which affect nervous system and is characterized with progressive distal motor neuron weakness. the survival motor neuron (smn) protein level reduces in patients with sma. two different genes code survival motor neuron protein in human genome. skeletal and intercostal muscles denervation lead to weakness, hypotony, hyporeflexia, respiratory fa...

actinomycosis is an indolent, slowly progressive infection caused by anaerobic or microaerophilic bacteria, primarily of genus actinomyces, which colonize the mouth, colon and vagina. mucosal disruption may lead to infection virtually at any sites in the body. the aim of this study was to underline different features of actinomycosis and to represent total data about etiologic agents, clinical,...

ebola virus disease (formerly known as ebola haemorrhagic fever) is a severe, often fatal illness, with a death rate of up to 90%. the illness affects humans and nonhuman primates (monkeys, gorillas, and chimpanzees). ebola first appeared in 1976 in two simultaneous outbreaks, one in a village near the ebola river in the democratic republic of congo, and the other in a remote area of sudan. the...

background: mccune albright syndrome is rare with an estimated prevalence of 1 in 100,000 to 1 in 1,000,000 persons. the classical clinical triad consists of fibrous dysplasia of the bone, café-au-lait skin spots and precocious puberty. however, in rare cases, there may be primary hypogonadism and amenorrhea. case presentation: an eighteen-year-old female presented with amenorrhea. she had a sh...

Introduction: Among different non-invasive approaches for determining the stability of the implant within the bone is to use a dynamic device called Periotest®.It is designed to provide objective measurement of tooth mobility. The aim of the present study is to evaluate the stress transfer and stability in short and standard dental implants using Periotest®</sup...

this study identifies and compares the antecedent of nigerian students’ perception on business social responsibility. part of its objectives is to examine the perception of business students in terms of importance of business social responsibility with respect to profitability, and the effectiveness of social responsibility in both long and short terms. the study reviews the related literature ...