We have previously reported that, depending on the dose, nitric oxide (NO)-generating agents exert a dual facilitatory and inhibitory action on glutamatergic transmission on the rostral ventrolateral medulla (RVLM) neurons. The molecular mechanisms underlying the NO-mediated synaptic inhibition have not yet been defined. Here we show that the amplitude of excitatory postsynaptic currents (EPSCs...

Nuclear DBF2p-related (NDR) kinases constitute a functionally conserved protein family of eukaryotic regulators that control cell division and polarity. In fungi, they function as effector kinases of the morphogenesis (MOR) and septation initiation (SIN) networks and are activated by pathway-specific germinal centre (GC) kinases. We characterized a third GC kinase, MST-1, that connects both kin...

A graph   is called integral if all eigenvalues of its adjacency matrix  are integers.  Given a subset $S$ of a finite group $G$, the bi-Cayley graph $BCay(G,S)$ is a graph with vertex set $Gtimes{1,2}$ and edge set ${{(x,1),(sx,2)}mid sin S, xin G}$.  In this paper, we classify all finite groups admitting a connected cubic integral bi-Cayley graph.

The Monte Carlo program, PYBBWH, is an implementation of the associated production of a charged Higgs and a W boson from bb̄ fusion in a general TwoHiggs-Doublet model for both CP-conserving and CP-violating couplings. It is implemented as a external process to Pythia 6. The code can be downloaded from http://www.isv.uu.se/thep/MC/pybbwh. 1 Associated H and W boson production The program, PYBBWH...

To make human immunodeficiency virus type 1 (HIV-1)-based vectors safer for use in the research and clinical setting, a significant modification to the HIV-1 genome has been the deletion of promoter and enhancer elements from the U3 region of the long terminal repeat (LTR). Vectors containing this deletion are thought to have no LTR-directed transcription and are called self-inactivating (SIN) ...

The fission yeast septation initiation network, or SIN, is a signal transduction network that is required for septum formation in Schizosaccharomyces pombe. Its activity is tightly regulated through the cell cycle, to ensure proper co-ordination of mitosis and cytokinesis. SIN signalling requires three protein kinases for its function and is mediated by a ras-superfamily GTPase. We discuss the ...

We calculate the geometrical and electronic structure of small Sin, Sin +, and Sin clusters up to sites n = 14 within a combined tight-binding-density-functional-theory scheme. Especially stable structures for n = 6 and 10 coincide with observed abundancies in the experimental mass spectra. All equilibrium structures are found to be close packed, with a different bonding than found in the bulk ...

We report the measurement of sin 2 W in ? N deep inelastic scattering from the NuTeV experiment. Using separate neutrino and anti-neutrino beams, NuTeV is able to determine sin 2 W with low systematic errors by measuring the Paschos-Wolfenstein variable R ? , a ratio of diierences of neutrino and anti-neutrino neutral-current and charged-current cross-sections. NuTeV measures sin 2 W (on?shell) =

This paper describes SiN, a new case-based planning algorithm that combines conversational case-based reasoning with generative planning. SiN is provably correct, and can do plan generation with an incomplete domain theory by using cases to extend that domain theory. SiN can also reason with imperfect world-state information, by incorporing preferences into the cases. We provide an empirical va...