Tetanic stimulation of skeletal muscle fibers elicits a train of spikes followed by a long-lasting depolarization called the late after-potential (LAP). We have conducted experiments to determine the origin of the LAP. Isolated single muscle fibers were treated with a high potassium solution (5 mM or 10 mM K) followed by a sudden reduction of potassium concentration to 2.5 mM. This procedure pr...

In this study, the joining of 6061-T6 aluminum alloy and DP590 steel using a M42 rivet via friction riveting technique is investigated. The surface morphology microstructure characterization reveal formation an anchor zone that imparts mechanical interlock as well metallurgical bonds at interface steel. A combination interlocking bonding results in achievement high load-carrying capacity 5.7 kN...

Motor imagery–based brain–computer interface (BCI) using electroencephalography (EEG) has demonstrated promising applications by directly decoding users’ movement related mental intention. The selection of control signals, e.g., the channel configuration and decoding algorithm, plays a vital role in the online performance and progressing of BCI control. While several offline analyses report the...

The continued investigations of the paranormal facilitated development novel theories and methodologies. Psi functioning living deceased in survival phenomena suggested agent psi (LAP) discarnate hypotheses, but neither has demonstrated sufficient explanatory power to claim superiority explaining data. Mediumship studies cannot determine whether information is sourced by means or LAP, presentin...

"Lipid accumulation product" (LAP) is a continuous variable based on waist circumference and triglyceride concentration previously associated with insulin resistance. We investigated the accuracy of LAP in identifying oral glucose tolerance test (OGTT) abnormalities and compared it to the homeostasis model assessment of insulin resistance (HOMA-IR) in a population of overweight/obese outpatient...

In this research, the effects of torque tightening on the stress distribution in double lap simple bolted and hybrid (bolted-bonded) joints have been investigated numerically. In order to determine the bolt clamping force value due to tightening torque in simple bolted and hybrid joints, which is necessary in numerical simulation, an experimental approach has been proposed. To do so, two kinds ...

In an innovative vision of manufacturing, orbital riveting is a joining technique characterized by high efficiency, energy saving, low costs and noise. It cold forming process where tool rotates at fixed angle (i.e., typically 3° to 6°) create sweeping line pressure around rivet. This movement progressively promotes, with each rotation, the collapse rivet shank down onto upper substrate joint, ...

Abstract Carbon fiber reinforced polymer (CFRP) with high specific strength, modulus, and other outstanding properties, which could be used in aerospace, shipbuilding, railway. The joint of carbon composite material plate metal plays an important role the overall performance structure. In this paper, a progressive damage model is developed based on laminate theory 3D Hashian theory. double bolt...

The phosphorylation state of transcription factors is a critical determinant of their function. C/EBPbeta occurs in cells as the transcriptional activator liver-enriched activating protein (LAP) and in the truncated form liver-enriched inhibitory protein (LIP) that inhibits transcription. Analysis of C/EBPbeta phosphorylation by isoelectric focusing (IEF) shows that LAP is present in multiple f...