نتایج جستجو برای: sinusoidal obstruction syndrome
تعداد نتایج: 684349 فیلتر نتایج به سال:
Purpose: Adverse reactions reported in patients treated with antibody-calicheamicin conjugates such as gemtuzumab ozogamicin (Mylotarg) and inotuzumab ozogamicin include thrombocytopenia and sinusoidal obstruction syndrome (SOS). The objective of this experimental work was to investigate the mechanism for thrombocytopenia, characterize the liver injury, and identify potential safety biomarkers....
Acute colonic pseudo-obstruction (ACPO), or Ogilvie’s syndrome, is an acute dilatation without mechanical obstruction; it most commonly seen in severely ill postoperative patients. While this syndrome has no clear pathophysiology, diagnosed when the cecum and right colon expand physical obstruction. This condition can lead to perforation intestinal ischemia. associated with a relatively high mo...
Asthma and chronic obstructive pulmonary disease (COPD) are highly prevalent chronic diseases in the general population. Both are characterized by similar mechanisms: airway inflammation, airway obstruction, and airway hyperresponsiveness. However, the distinction between the two obstructive diseases is not always clear. Multiple epidemiological studies demonstrate that in elderly people with o...
Dear Sirs, Although haematopoietic stem cell transplantation (HSCT) is being used for haematopoietic reconstitution following highdose chemotherapy for malignancy, it involves some serious transplant-related complications (1, 2), such as graft-versushost disease (GVHD) and vascular disorders (such as veno-occlusive disease (VOD), pulmonary vasculopathy, thrombotic microangiopathy (TMA), and cap...
Recipients of hematopoietic stem cell transplantation (HSCT) frequently have iron overload resulting from chronic transfusion therapy for anemia. In some cases, for example, in patients with myelodysplastic syndromes and thalassemia, this can be further exacerbated by increased absorption of iron from the gut as a result of ineffective erythropoiesis. Accumulating evidence has established the n...
During chemotherapy for childhood acute lymphoblastic leukemia, all organs can be affected by severe acute side effects, the most common being opportunistic infections, mucositis, central or peripheral neuropathy (or both), bone toxicities (including osteonecrosis), thromboembolism, sinusoidal obstruction syndrome, endocrinopathies (especially steroid-induced adrenal insufficiency and hyperglyc...
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