نتایج جستجو برای: situ forming sol

تعداد نتایج: 261055  

Journal: :The Journal of pharmacology and experimental therapeutics 1997
D D Rees J D Brain M E Wohl J L Humes R A Mumford

Elastases in cystic fibrosis (CF) pulmonary fluids damage lung tissue and perpetuate cycles of infection, inflammation and injury. Elastases from three different sources may be present in CF airways: neutrophils, macrophages and Pseudomonas. We measured how well the cephalosporin-based antielastase L-658,758 blocks the activity of human neutrophil elastase (NE), human proteinase-3, human macrop...

Journal: :Frontiers in Bioengineering and Biotechnology 2016

Journal: :Minerals 2023

Aluminum is a significant impurity in the ion-adsorption rare earth ore. The changes occurrences of aluminum have great influence on leaching In this paper, column method was employed using magnesium sulfate as agent to investigate effects pH and concentration earths. results show that at low concentrations, earths greatly enhanced, while not significantly affected by decrease agent. At high sl...

Journal: :European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017
Justine Thiry Miranda G M Kok Laurence Collard Antoine Frère Fabrice Krier Marianne Fillet Brigitte Evrard

Solid dispersion formulations made of itraconazole (ITZ) and Soluplus® (polyethylene glycol, polyvinyl acetate and polyvinylcaprolactame-based graft copolymer abbreviated SOL) were produced using hot melt extrusion. Since ITZ possesses a water solubility of less than 1ng/mL, the aim of this work was to enhance the aqueous solubility of ITZ, and thereby improve its bioavailability. The three for...

Journal: :Neuron 2012
Rui Wang Jerry E. Mellem Michael Jensen Penelope J. Brockie Craig S. Walker Frédéric J. Hoerndli Linda Hauth David M. Madsen Andres V. Maricq

The neurotransmitter glutamate mediates excitatory synaptic transmission by gating ionotropic glutamate receptors (iGluRs). AMPA receptors (AMPARs), a subtype of iGluR, are strongly implicated in synaptic plasticity, learning, and memory. We previously discovered two classes of AMPAR auxiliary proteins in C. elegans that modify receptor kinetics and thus change synaptic transmission. Here, we h...

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