The clinical treatment of large, full-thickness skin injuries with tissue-engineered autologous dermo–epidermal substitutes is an emerging alternative to split-thickness grafting. However, their production requires about one month in vitro cell and tissue culture, which a significant drawback for the patients severe defects. With aim reduce time, we developed new dynamic bioreactor setup that a...

Abstract Hidradenitis suppurativa (HS) is a chronic recurrent debilitating condition. It characterized by abscesses, and can be complicated rupture, scarring sinuses. The management of HS multidisciplinary, involving general lifestyle modification, medical treatment, surgery. A wide range surgical interventions have been described for disease control management. However, strategies are highly v...