The purpose of this research was to develop and evaluate multiparticulates of alginate and chitosan hydrogel beads exploiting pH sensitive property for colon-targeted delivery of theophylline. Alginate and chitosan beads were prepared by ionotropic gelation method followed by enteric coating with Eudragit S100. All formulations were evaluated for particle size, encapsulation efficiency, swellab...

The printed Biomaterial Laboratory at UTEP does research a printable hydrogel which can have appropriate properties for tissue engineering of the skin. Skin is the largest organ in our body which protects us from the environment and pathogens. Skin can be affected by burns and also by diabetic foot ulcers. The current tissue engineered skin substitutes for treatment of diabetic foot ulcers have...

The aim of this study was to investigate the effects of Sodiume alginate edible coating with concentrations of 0/25, 1/25, 0/75 and 1/75% (W/V) on chemical changes of dressed Kilka during frozen storage. Prepared samples of Kilka fish have been coated for 1 h with the dipping method. Coated and uncoated samples have been packed in polyethylene dishes with selphon coverage (75 packs of 250 g). C...

Probiotic microorganisms are incorporated into a wide variety of foods, supplements, and pharmaceuticals to promote human health and wellness. However, maintaining bacterial cell viability during storage and gastrointestinal transit remains a challenge. Encapsulation of bifidobacteria within food-grade hydrogel particles potentially mitigates their sensitivity to environmental stresses. In this...

The aim of the present study was to develop and characterize coated chitosan-alginate beads containing cefaclor as a controlled release delivery system. Coated cefaclor beads were prepared by solvent evaporation techniques. Beads were found to be intact and spherical in shape. Their size range was 1.05 to 2.06. The loading efficiency showed maximum value when the concentration of cefaclor, chit...

In this paper, different formulation types of microparticulate systems such as beads, microbeads, microspheres and microsponges using to special attention chitosan, alginate and eudragit RS 100 are reviewed. Chitosan and alginates are natural, anionic or cationic, biocompatible, biodegredable and non-toxic polymers. They have excellent potential for pharmaceutical and biopharmaceutical applicat...

A large supply of air free from micro-organisms is needed for certain modern commercial processes, such as submerged fermentations, which depend upon aeration and the control of infection. Consequently, it is necessary to test this air for sterility. Most methods of estimation are unsuited to lengthy tests and to large quantities of air, for instance the membrane filter (Haas, 1956), which, tho...

Composite materials based on a titanium support and a thin, alginate hydrogel could be used in bone tissue engineering as a scaffold material that provides biologically active molecules. The main objective of this contribution is to characterize the activation and the functionalization of titanium surfaces by the covalent immobilization of anchoring layers of self-assembled bisphosphonate nerid...

Immobilization of cyanobacterium Spirulina platensis in sodium alginate (1.5 %) gave the best quality of bead and 15-16 beads were formed per mL of aqueous solution of alginate. The immobilized cells were used in a batch process for treatment of diluted sewage. After 8 days, 95 % of BOD5, 77 % of COD, 90 % of ammonia, and 94 % of TSS were removed.