نتایج جستجو برای: sodium arsenite

تعداد نتایج: 189190  

Journal: :Environmental Health Perspectives 1994
T C Lee I C Ho

Human fibroblasts (HFW) were 10-fold more susceptible than Chinese hamster ovary (CHO-K1) cells to sodium arsenite. Comparison of cellular antioxidant enzyme activities showed that CHO-K1 cells contained 3- and 8-fold more glutathione-peroxidase and catalase activities, respectively, than HFW cells. Since vitamin E, methylamine, and benzyl alcohol could prevent, in part, the arsenite-induced ki...

2013
ADEWALE ADETUTU OLUSOJI ABIODUN OWOADE OLUBUNMI SIMEON OYEKUNLE

Aims and Objectives: The effectiveness of crude methanolic extracts of Bridelia ferruguinea, Tridax procumbens, Ocimum gratissimum and Lawsonia inermis against clastogenicity induced by sodium arsenite (SA) was evaluated using an in-vivo rat bone marrow cell micronuclei test and the DPPH radical scavenging assay. Methods: 50 mg/kg body weight of the extracts were given by gavaging to the rats i...

Journal: :Cancer research 2007
Vladimir N Ivanov Hongning Zhou Tom K Hei

Melanoma is the most lethal form of skin cancer. There is a lack of effective treatments for individuals with advanced disease. Many melanomas exhibit high levels of radioresistance. The direct consequence of gamma-irradiation for most melanoma cells is growth arrest at the G2-M phase of cell cycle. However, radiation-induced signaling pathways may affect numerous additional targets in cancer c...

2017
Hasina Perveen Moumita Dash Shamima Khatun Moulima Maity Syed Sirajul Islam Sandip Chattopadhyay

Momordica charantia (MC) fruit known as bitter gourd, is of potential nutritional and medicinal value. The objectives of the present in vitro study were to evaluate the efficacy of bioactive pectic polysaccharides (CCPS) of MC along with another well-known bioactive compound curcumin in the abrogation of hepatocellular oxidative stress persuaded by sodium arsenite. Electrozymographic method was...

2012
Arnab Bhattacharya Pushpa Dhar Raj D. Mehra

The effects of sodium arsenite exposure on the hepatic maturation period of cellular and functional reorganization in developing rat livers were evaluated. Animals received intraperitoneal injections of sodium arsenite (1.5 mg/kg body weight) or distilled water on days 9 to 28 after birth. On day 29, the animals were sacrificed either by cervical dislocation or by perfusion fixation. The perfus...

Journal: :Molecular and cellular biology 2008
Jung-Eun Kim Incheol Ryu Woo Jae Kim Ok-Kyu Song Jeongeun Ryu Mi Yi Kwon Joon Hyun Kim Sung Key Jang

The repression of translation in environmentally stressed eukaryotic cells causes the sequestration of translation initiation factors and the 40S ribosomal subunit into discrete cytoplasmic foci called stress granules (SGs). Most components of the preinitiation complex, such as eIF3, eIF4A, eIF4E, eIF4G, and poly(A)-binding protein, congregate into SGs under stress conditions. However, the mole...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1985
F Lawrence M Robert-Gero

The induction of heat shock proteins in three species of Leishmania, L. tropica, L. enrietti, and L. donovani is reported. When cultures of promastigotes are shifted from 26 degrees C to 37 degrees C or 40 degrees C, the synthesis of proteins with apparent molecular weights of 88,000, 74,000, and 54,000 is stimulated. Actinomycin D added just prior to the shift prevented the appearance of these...

2016
Randhir Kumar T.K. Banerjee

The impact of sublethal toxicity of sodium arsenite on hematological and certain biochemical parameters of the fresh water catfish Clarias batrachus has been analyzed following exposure of sublethal concentration (1 mg/L; 5% of LC50 value) of sodium arsenite for 10, 30, 45, and 60 days. Arsenic bioaccumulation in the blood tissue of the fish increased progressively with increased period of expo...

2013
J. K. Oloke E. O. Akanni V. A. Togun

This study investigated the Immunomodulating activity of Rhizopus nigricans meal with a view of comparing it with that exhibited by -glucan. The indicators of the immunomodulating activity employed in this study were: hormonal assay (testosterone estimation), testis homogenization (elongated spermatids evaluation) and internal organs histological examinations. R. nigricans meal supplementation ...

Journal: :The Analyst 1998
J C Ng D Johnson P Imray B Chiswell M R Moore

A hydride cold-trapping technique was developed and optimised for the measurement of urinary arsenic metabolites. The analytical precision of the method was found to be 6.1, 4.0 and 4.8% (n = 5) for inorganic arsenic (ASi), monomethylarsonate (MMA) and dimethylarsinate (DMA), respectively, with recoveries close to 100%. The detection limits were 1.0, 1.3 and 3 ng for ASi, MMA and DMA, respectiv...

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