Phenytoin, a voltage-gated sodium channel (NaV channel) antagonist, reportedly inhibits arginine vasopressin (AVP) release from an isolated rat neurohypophysis. So far, it is uncertain whether phenytoin has a direct action on ectopic AVP-producing neuroendocrine tumors. We studied the effect of phenytoin on the release of copeptin, the C-terminal fragment of pro-AVP, and expression of AVP gene ...

Changes in sodium intake exert well-defined and opposite effects on adrenal and vascular responsiveness to angiotensin n (All). Whereas the adrenal glomerulosa zone becomes more sensitive to All during sodium restriction, vascular sensitivity to All is decreased during sodium restriction and increased by sodium loading. The extent to which regulation of smooth muscle All receptors is involved i...

Net sodium influx under K-free conditions was independent of the intracellular sodium ion concentration, [Na](i), and was increased by ouabain. Unidirectional sodium influx was the sum of a component independent of [Na](i) and a component that increased linearly with increasing [Na](i). Net influx of sodium ions in K-free solutions varied with the external sodium ion concentration, [Na](o), and...

The arginine vasopressin-induced increase in intracellular sodium concentration was augmented in cultured rat vascular smooth muscle cells derived from 12-week-old spontaneously hypertensive rats (SHR) compared with those from 12-week-old normotensive Wistar-Kyoto (WKY) rats. This difference was enhanced by treatment with a Na+,K(+)-ATPase inhibitor, ouabain. The calcium-free state did not affe...

Erratum The original version of this article [1] unfortunately contained a mistake. The formula concentration described in the “Treatments” section was provided incorrectly. The corrected text is available below: “The SBCG1 treatment was a solution with sodium bicarbonate and calcium gluconate, both at a concentration of 0.75 % (w/v); and SBCG2 had the same concentration of sodium bicarbonate t...

Abstract In this study, the silver extraction potential from waste x-ray films using sodium hydroxide and nitric acid was studied. Sodium of different concentrations were used as stripping solutions to determine optimum leaching concentration. Optimum time temperature also investigated by varying temperatures, respectively. The stripped analysed for concentration Flame Atomic Absorption Spectro...

-1 . Dehydration of toads with empty bladders causes elevation of the sodium concentration (C) of their plasma according to the relationship : original water content C = Co x original water contentwater deficit' where Co is the plasma sodium concentration of the hydrated toad and volumes are expressed as ml/100 g of hydrated toad. 2. The concentration of potassium in the plasma declines in the ...

The membrane potential in the dark and the saturated response height of the ventral nerve photoreceptor of Limulus was measured by an intracellular electrode while the external concentra­ tion of calcium, magnesium and sodium ions was varied. Decreasing the extracellular calcium concentration from 10-2 mol/1 causes a calcium-dependent lowering of the dark membrane potential and at very low conc...