We report two Australian patients with soft tissue infections due to Photorhabdus species. Recognized as important insect pathogens, Photorhabdus spp. are bioluminescent gram-negative bacilli. Bacteria belonging to the genus are emerging as a cause of both localized soft tissue and disseminated infections in humans in the United States and Australia. The source of infection in humans remains un...

Fournier’s gangrene is a life-threatening soft-tissue infection of the perineum requiring radical soft-tissue debridement and antibiotic therapy. We report a 24-year follow-up of a patient with Fournier’s gangrene treated with subcutaneous unilateral testicle implantation following contralateral orchiectomy and radical debridement. Hormonal testicular function was preserved despite the subcutan...

We investigated the distribution of the broad-spectrum antibiotic fosfomycin in infected soft tissue of patients with uncomplicated cellulitis of the lower extremities or diabetic foot infection using in vivo microdialysis. Our findings suggest that fosfomycin exhibits good and similar penetration into the fluid in the interstitial space in inflamed and noninflamed soft tissue in patients.

Various options are available for restoring anterior teeth. Their choice is dictated by the severity of infection of the teeth to be extracted and the pocket depth. Immediate single-stage implant placement proved to be the least traumatic option, which best preserved the soft tissue. A differential use of surgical and prosthodontic techniques is indispensable to account for conditions in the in...

  Introduction: Ubiquicidin (UBI) 29-41 is a synthetic antimicrobial peptide that binds with the microbial cell membrane at the location of infection. This study was conducted to evaluate its probable efficacy as an infection-imaging agent with potential to differentiate bacterial infection from sterile inflammation in humans. Methods: Fifteen diabetic foot patients ...

Descending necrotizing mediastinitis a clinical entity formed by the spreading of cervical infection from dental and oropharyngeal structures through deep cavities between fascia on neck to mediastinum, pleural pericardial spaces with necrosis soft tissue has high mortality. Herein we present case 73-year-old admitted emergency department septic clinic. The patient was diagnosed descending due ...

AIM To evaluate the results of the Ilizarov method in management of cases with bone loss, soft tissue loss and infection. METHODS Twenty eight patients with severe leg trauma complicated by bone loss, soft tissue loss and infection were managed by distraction osteogenesis in our institution. After radical debridement of all the infected and dead tissues the Ilizarov frame was applied, cortico...