the application of laser in dentistry is considered as a favorable technique for patients due to its many advantages compare to other current methods. one of the main goals in pediatric dentistry is to provide the treatment as comfortable as possible without any risks for the care. laser is being used in different pediatric dental conditions including caries detection, caries removal and cavity...

Malignant gastrointestinal neuroectodermal tumor (GNET) is an infrequent soft-tissue sarcoma, formerly referred to as clear-cell sarcoma-like (CCSLGT) and frequently reported in the literature sarcoma of tract (CCS-GI); it characterized by absence melanocytic differentiation presence nontumoral osteoclast-like giant cells (OLGCs). The current study reports a case 79 year old woman admitted emer...

Multicatheter brachytherapy can be applied as a monotherapy or in combination with external beam radiotherapy as an adjuvant treatment for soft tissue sarcoma. Successful application of brachytherapy in the treatment of soft tissue sarcoma requires implementation of multiple imaging modalities during preoperative and postoperative planning. Preoperative imaging is essential in planning local th...

pancreatic neuroendocrine tumors (pnet) are uncommon pancreatic neoplasms, accounting for 1-2% of all pancreatic tumors. however, they have a better prognosis and long-term survival compared to exocrine pancreatic cancer. pnets can be divided into functional or non-functional based upon whether or not they excrete active substances relevant to specific clinical syndromes. skeletal muscle metast...

PURPOSE Hypoxia is associated with malignant progression and poor outcome in several human tumors, including soft tissue sarcoma. Recent studies have suggested that carbonic anhydrase (CA) IX is an intrinsic marker of hypoxia, and that CA IX correlates with poor prognosis in several types of carcinoma. The aim of this study was to quantify the extent of CA IX expression and to investigate wheth...

Extraosseous osteogenic sarcoma is a very rare malignant neoplasm. Out of the more than 400 cases of soft tissue sarcomas on file in our hospital, only 2 were extraosseous osteogenic sarcomas. Both were situated in the thigh. The first case was initially diagnosed as a hematoma and treated by marginal excision. The diagnosis of high-grade osteosarcoma primarily arising in soft tissue was made f...

In the present study, a case was reported concerning a patient with a bulky extremity soft tissue sarcoma treated with spatially fractionated Grid therapy and then followed by standard external beam radiotherapy. Treatment was performed using a Grid block to deliver 15 Gy in one fraction. There was one week interval break before EBRT treatment with 50 Gy in 25 fractions for the neoadjuvant exte...

Podoplanin is a 38 kDa mucin-type transmembrane glycoprotein that was first identified in rat glomerular epithelial cells (podocytes). It is expressed in normal lymphatic endothelium, but is absent from vascular endothelial cells. D2-40 is a commercially available mouse monoclonal antibody which binds to an epitope on human podoplanin. D2-40 immunoreactivity is therefore highly sensitive and sp...