BACKGROUND Repetitive endothelial damage from dialysis membrane incompatibility is a probable cause of accelerated atherosclerosis in haemodialysis patients. Consequently pulse wave velocity (PWV), a measure of arterial stiffness, was utilized as a surrogate marker of vascular dysfunction during dialysis with two commonly used synthetic dialysers. METHODS PWV was monitored before, during and ...

The zinc finger protein EVI1 is causally associated with acute myeloid leukemogenesis, and inhibition of its function with a small molecule therapeutic may provide effective therapy for EVI1-expressing leukemias. In this paper we describe the development of a pyrrole-imidazole polyamide to specifically block EVI1 binding to DNA. We first identify essential domains for leukemogenesis through str...

The amount of petroleum hydrocarbon and heavy metals in the sediment of the Persian Gulf’s shore, at 8 selected stations were determined and showed the maximum of 143.6 and 58.6 mg/kg sediment, respectively, both maximum amounts were related to Emam Hassan zone which is located at 50 kilometers to west Boushehr port. Bioremediation of contaminated sediment were studied in slurry and solid-state...

We studied the composition-dependent miscibility of polyamide 6 and biobased 4,10 (PA6/PA410) blends, as triggered by crystallization driven phase segregation. The blends were prepared extrusion in a wide composition range characterized X-ray diffraction (both in-situ ex-situ SAXS/WAXS), Differential Scanning Calorimetry (DSC), Polarized Light Optical Microscopy (PLOM) during non-isothermal cry...

We present a solid state accelerator concept utilizing particle acceleration along crystal channels by longitudinal electron plasma waves in a metal. Acceleration gradients of order 100 GV/cm are theoretically possible, but channeling radiation limits the maximum attainable energy to lo5 TeV for protons. Beam dechanneling due to multiple scattering is substantially reduced by the high accelerat...

Emission and absorption spectra of many organic dyes in liquid solutions depend on the local electric fields generated by the surrounding polar solvent molecules. This “solvation effect” is a result of intermolecular solutesolvent interaction forces (such as dipole-dipole or dipole-induced dipole) that tend to stretch molecular bonds and shift charge distribution on molecules, altering the ener...

Some years ago I developed an interest in Tesla coils. I was teaching a senior elective course at Kansas State University where we talked about power MOSFETs and topics related to high voltages and currents. I decided to use a Tesla coil as a class project. We would talk about design aspects, then design, build, and test a coil. The best description of the results of that plan was fiasco, or ma...