BACKGROUND Individuals with acquired phonological dyslexia experience difficulty associating written letters with corresponding sounds, especially in pseudowords. Previous studies have shown that reading can be improved in these individuals by training letter-sound correspondence, practicing phonological skills, or using combined approaches. However, generalization to untrained items is typical...

Nanopore DNA sequencing via transverse current has emerged as a promising candidate for third-generation sequencing technology. It produces long read lengths which could alleviate problems with assembly errors inherent in current technologies. However, the high error rates of nanopore sequencing have to be addressed. A very important source of the error is the intrinsic noise in the current ari...

A neuronal model intended to target highly sonorant periods of a speech stream is presented. The model—“Spike-V”—uses habituation and Hebbian learning in opposition to each other to dynamically adjust its behavior. Acting in realtime, driven by only the signal, Spike-V produces a spike-train in which each spike corresponds to roughly the center of a period of high sonority (i.e. a vowel) in the...

This paper provides an Optimality-Theoretic analysis of a number of Russian vowel reduction patterns. In particular, the analysis presented here relies on a non-unitary approach (Crosswhite 1999) to two-pattern vowel reduction systems, such as those typically seen in Russian dialects. Furthermore, a particularly complex dialectal pattern, traditionally referred to as "dissimilative" reduction, ...

objective: leishmaniasis is caused by parasitic protozoa of the genus leishmania which in the infected host is obligate intracellular parasite. lack gene is conserved among related leishmania species. lack is the immuno-dominant antigen of l.major which is considered as the most promising molecule for a recombinant or dna vaccine against leishmaniasis. materials and methods: in this study the ...

The term 'shotgun metagenomics' is applied to the direct sequencing of DNA extracted from a sample without culture or target-specific amplification or capture. In diagnostic metagenomics, this approach is applied to clinical samples in the hope of detecting and characterizing pathogens. Here, I provide a conceptual overview, before reviewing several recent promising proof-of-principle applicati...

trichophyton rubrum (t. rubrum) is an anthropophilic dermatophyte that is distributed worldwide and causes common cutaneous disease such as mycosis. although several properties of this fungus have been investigated so far, however a few studies were carried out in the field of molecular biology of this fungus. in the present study we tried to identify its molecular characterization of the goano...

We address the question of the relationship between two time series associated to the speech signal. The first one is the sonority function which was introduced in Galves et al. (2002) as an index of the local regularity of the speech signal. The second time series is the intra-oral pressure during the production of speech. We argue that the joint evolution of both time series can be well descr...