BACKGROUND & AIMS High-resolution manometry with spatiotemporal representation of pressure data is a technique that has developed during the past 10-15 years. We compared spatiotemporal and traditional line plot representation of manometry data in a group of medical students in terms of the ability of the user to come to a rapid and accurate diagnosis and evaluated user preferences for the 2 fo...

Despite the number of proposals for processing 2D spatial data, the areas of 3D spatial information is still quite empty. Moreover, only few attempts appear towards incorporating the temporal and the 3D spatial domains. At the same time the vast growth of Internet and WWW has set a new domain for applications. One of the most promising Web browser plug-ins is VRML, the means for 3D spatial navi...

Bistability is considered wide-spread among bacteria and eukaryotic cells, useful, e.g., for enzyme induction, bet hedging, and epigenetic switching. However, this phenomenon has mostly been described with deterministic dynamic or well-mixed stochastic models. Here, we map known biological bistable systems onto the well-characterized biochemical Schlögl model, using analytical calculations and ...

Multivalency has an important but poorly understood role in molecular self-organization. We present the noncovalent synthesis of a multicomponent supramolecular polymer in which chemically distinct monomers spontaneously coassemble into a dynamic, functional structure. We show that a multivalent recruiter is able to bind selectively to one subset of monomers (receptors) and trigger their cluste...

One of the most common problems faced by designers of wireless communication systems is the spatiotemporal variations in the wireless channel which arise mainly due to the phenomenon of multipath fading which is inevitable in scattering environments that are subject to changes over time. A wide variety of pre/post processing techniques have been used to mitigate the degrading effects of such ch...

The design of multiagent simulations devoted to complex systems, addresses the issue of modeling behaviors that are involved at different space, time, behavior scales, each one being relevant so as to represent a feature of the phenomenon. We propose here a generic formalism intended to represent multiple environments, endowed with their own spatiotemporal scales and with behavioral rules for t...

Turbulence induced by Rayleigh-Taylor instability is a ubiquitous phenomenon with applications ranging from atmospheric physics and geophysics to supernova explosions and plasma confinement fusion. Despite its fundamental character, a phenomenological theory has been proposed only recently and several predictions are untested. In this Rapid Communication we confirm spatiotemporal predictions of...

Binocular rivalry is a fascinating perceptual phenomenon that has been characterized extensively at the psychophysical level. However, the underlying neural mechanism remains poorly understood. In particular, the role of the early visual pathway remains controversial. In this study, we used voltage-sensitive dye imaging to measure the spatiotemporal activity patterns in cat area 18 evoked by di...

Meso-scale turbulence is an innate phenomenon, distinct from inertial turbulence, that spontaneously occurs at low Reynolds number in fluidized biological systems. This spatiotemporal disordered flow radically changes nutrient and molecular transport in living fluids and can strongly affect the collective behaviour in prominent biological processes, including biofilm formation, morphogenesis an...

The design of multiagent simulations devoted to complex systems, addresses the issue of modelling behaviors that are involved at different space, time, behavior scales, each one being relevant to represent a feature of the phenomenon. We propose here a generic formalism intented to represent multiple environments, endowed with their own spatiotemporal scales and with behavioral rules for the ag...