نتایج جستجو برای: specific enolase

تعداد نتایج: 1037605  

Journal: :Acta biochimica Polonica 2004
Joanna B Trojanek Maria M Klimecka Anna Fraser Grazyna Dobrowolska Grazyna Muszyńska

A protein kinase of 57 kDa, able to phosphorylate tyrosine in synthetic substrates pol(Glu4,Tyr1) and a fragment of Src tyrosine kinase, was isolated and partly purified from maize seedlings (Zea mays). The protein kinase was able to phosphorylate exogenous proteins: enolase, caseins, histones and myelin basic protein. Amino acid analysis of phosphorylated casein and enolase, as well as of phos...

2014
Jeremy M. Sternberg Julia A. Mitchell

BACKGROUND This study was carried out to determine the potential of neuronal specific enolase (NSE) as a stage diagnostic marker in human African trypanosomiasis. METHODS Plasma and cerebrospinal fluid were obtained from a cohort of Trypanosoma brucei rhodesiense-infected patients and non-infected controls. Neuronal specific enolase concentrations were measured by ELISA and analysed in relati...

Journal: :Free radical biology & medicine 2006
Yumin Chen Chotiros Daosukho Wycliffe O Opii Delano M Turner William M Pierce Jon B Klein Mary Vore D Allan Butterfield Daret K St Clair

Adriamycin (ADR) is a potent anticancer drug, but its use is limited by a dose-dependent cardiotoxicity. Oxidative stress is regarded as the mediating mechanism of ADR cardiotoxicity. However, cardiac proteins that are oxidatively modified have not been well characterized. We took a redox proteomics approach to identify increasingly oxidized murine cardiac proteins after a single injection of A...

2015
Tjasa Vizin Janko Kos

BACKGROUND Gamma-enolase, known also as neuron-specific enolase (NSE), is an enzyme of the glycolytic pathway, which is expressed predominantly in neurons and cells of the neuroendocrine system. As a tumour marker it is used in diagnosis and prognosis of cancer; however, the mechanisms enrolling it in malignant progression remain elusive. As a cytoplasmic enzyme gamma-enolase is involved in inc...

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