Three-dimensional (3D) simulations using the smoothed particle hydrodynamics (SPH) method were performed for smooth and stepped spillways with converging walls, in order to evaluate influence of wall deflection step macro-roughness on main non-aerated flow properties. The encompassed a 1V:2H sloping spillway, convergence angles 9.9° 19.3°, discharges corresponding skimming regime, chute. overal...

Activation of the PDGF receptor on human arterial smooth muscle cells (SMC) induces migration and proliferation via separable signal transduction pathways. Sphingosine-1-phosphate (Sph-1-P) can be formed following PDGF receptor activation and therefore may be implicated in PDGF-receptor signal transduction. Here we show that Sph-1-P does not significantly affect PDGF-induced DNA synthesis, prol...

We present a particle method for the simulation of three dimensional compressible hydrodynamics based on a hybrid Particle-Mesh discretization of the governing equations. The method is rooted on the regularization of particle locations as in remeshed Smoothed Particle Hydrodynamics (rSPH). The rSPH method was recently introduced to remedy problems associated with the distortion of computational...

Sphingosine (Sph) has been implicated as a modulator of membrane signal transduction systems and as a regulatory element of cardiac and skeletal muscle physiology, but little information is presently available on its precise mechanism of action. Recent studies have shown that sphingosine 1-phosphate (S1P), generated by the action of sphingosine kinase (SphK) on Sph, also possesses biological ac...

OBJECTIVES We assessed the characteristics of self-perception of health (SPH) in relation to psychological distress and physical symptoms, and willingness of servicemen to see their Medical Officer (MO) by their SPH rating. DESIGN We randomly selected 4,500 servicemen to receive either a full or an abridged screening questionnaire. MEASURES The full questionnaire included 6 items from the s...

In this paper, we propose an interactive method based on Smoothed Particle Hydrodynamics (SPH) to simulate blood as a fluid with free surfaces. While SPH was originally designed to simulate astronomical objects, we gear the method towards fluid simulation by deriving the force density fields directly from the Navier-Stokes equation and by adding a term to model surface tension effects. In contr...

The smoothed particle hydrodynamics method has been deeply studied and validated for the past decades on a weakly-compressible fluid discretization for the Euler equations. Recently several authors have proposed the use of SPH truly-incompressible algorithms in the most varied domains of computational fluid dynamics. Within this technique, based on the projection method, a pressure Poisson equa...

For the fast transient dam break flooding with floating bodies presented through intricate city layouts, the traditional grid-based method based on solving two dimensional (2D) Shallow Water Equations or three dimensional (3D) Reynolds-averaged Navier-Stokes equations have difficulty in modelling the 3D unsteady flow features and the moving objects in the flow, causing inaccuracies. In this pap...

In this paper, we have investigated the ability of smoothed particle hydrodynamics (SPH) to simulate turbulent flows. It is well known that the standard method without corrections cannot predict the energy cascade of a turbulent flow. In the absence of viscosity, standard SPH simulations produce purely noisy particle motion and at finite viscosities the method overpredicts dissipation. As a rem...