stem cell therapy can be useful for spinal cord injury (sci). induced pluripotent stem cells (ipscs) are generated by reprogramming mature, fully differentiated cells into a pluripotent state. the ability to generate pluripotent cells from adult somatic cells without the need for an embryo was a major development in stem cell biology. ipscs were established from mouse fibroblasts and demonstrat...

objective(s) recent studies revealed the neuroprotective effects of epigallocatechin gallate (egcg) on a variety of neural injury .the purpose of this study was to determine the effects of egcg on the tissue lipid peroxidation after spinal cord injury (sci). materials and methods rats were randomly divided into four groups of 7 rats each as follows: sham-operated group, trauma group, and egcg-t...

bone marrow mesenchymal stem cells can differentiate into neurons and astrocytes after transplantation in the spinal cord injury of rats. although bone marrow mesenchymal stem cells are known to protect against spinal cord injury through anti-apoptotic effects, but generation of neural stem cells with large number and safety protocols unclear. in the present study, described the differentiation...

Introduction The spinal cord is an important part of the central nervous system (CNS), and assessment of this structure is essential for the work-up of certain diseases, including multiple sclerosis, spondylosis, and trauma. However, there are a few challenges in imaging the spinal cord, including its small size, motion of the cord caused by cardiac pulsation, cerebrospinal fluid (CSF) flow, an...

clear cell variant of ependymoma is almost exclusively located in the supratentorial region. only few cases of this tumor that located in the spinal cord have been reported. here we report one case of intramedullary clear cell ependymoma of the lumbar spinal cord. in microscopic examination, the tumor cells were round to oval with moderate amounts of clear cytoplasm and centrally located large ...

a retrospective analysis was performed on forty cases of spinal cord meningiomas, operated on at dr. shariati hospital from 1976 to 1990. age and sex distribution, clinical presentation and tumor location were comparable to those reported by others. in males the tumors were distributed evenly in cervical and dorsal areas and were often anterior to the cord. this finding makes a different surgic...

introduction: cell transplantation is one of the main strategies for spinal cord injury repair. as oecs of the olfactory mucosa can be obtained by simple biopsy in all individuals without affecting their smell sensation, oecs considered as a promising candidate for autologous transplantation in the nervous system injury, especially for spinal cord repair. thereby in the current study oecs were ...

background: the present study was designed to evaluate the secondary microglial activation processes after spinal cord injury (sci). methods: a quantitative histological study was performed to determine ed-1 positive cells, glial cell density, and cavitation size in untreated sci rats at days 1, 2, and 4, and weeks 1, 2, 3, and 4. results: the results of glial cell quantification along the 4900...