We describe a case of spinal leptomeningeal metastases of an astrocytoma of the conus medullaris that presented with quadriplegia. The patient was a 50-year-old woman with a previously treated astrocytoma of the conus medullaris and a spinal cord metastasis at the Th2-L level. Four years after the initial treatment, the patient developed weakness of the upper extremities with a decreased muscul...

Many intracranial malign tumors including glioblastomas, malign astrocytomas. medulloblastomas. some of the pineal region tumors and ependymomas have a high potential for metastasis (3.4,11). These tumors usually spread via the cerebrospinal fluid pathways and locate on the surface of the spinal cord. Pure intramedullary location of a metastatic mass from medulloblastoma is a very rare patholog...

Two cases of very rare intramedullary spinal cord metastasis from colon carcinoma and renal carcinoma were treated primarily by microsurgical excision. A 44-year-old female presented with colon carcinoma metastasis manifesting as complete neurological deficit. She had undergone colon resection 2 years previously for colon carcinoma. The tumor was excised by microsurgery with megadose steroid th...

Spinal metastases may present in a myriad of ways, most commonly back pain with or without neurology. We report an unusual presentation of isolated atypical chest pain preceding metastatic cord compression, secondary to penile carcinoma. Spinal metastasis from penile carcinoma is rare with few cases reported. This unusual presentation highlights the need for a heightened level of clinical suspi...

experimental allergic encephalomyelitis (eae), a demyelinating disease induced in the animals parallels multiple sclerosis in human in several aspects, provides a useful model to investigate multiple sclerosis. in this study, we have therefore used this model to study functions of nerve growth factor (ngf) in eae. ngf with considerable effects on neuron survival, proliferation and differentiati...

the prevalence of spinal cord injury (sci) is about 2.5 million in the worldwide and more than 130,000 new injuries reported each year. regeneration in the cns versus the pns is very different from the other tissues and many factors can prevent regeneration in pns and specially cns. previous researches demonstrated that regeneration of cns can inhibit by inhibitory molecules and glial scar. the...

spinal cord injury (sci) is a devastating condition with enormous personal and social costs. to develop preventive strategies, the determination of epidemiological features and causes is required. due to iran's high incidence of road traffic crash (rtc) injuries, epidemiologic data concerning specific causes of sci may assist in reducing this national health dilemma. in a retrospective stu...

spinal cord injuries (sci) are highly disabling and injuries. this study aims to describe the demographic and epidemiologic data on auto accident patients who were admitted at khatam alanbia hospital. the results obtained from 73 sci patients treated on the sci inpatient units of the khatam alanbia hospital (from march 2009 to march 2013) were evaluated retrospectively. then patient gender, age...

a 21-year old man with cervical spinal cord damage due to diving was admitted in the icu. tracheostomy was performed due to prolonged mechanical ventilation. left lung atelectasis happened frequently. because of the difficulty of bronchoscopy and failing of recruitment, using a double lumen, two tracheal tubes were guided into the left and right lungs through the tracheostomy stoma site. after ...

introduction: spinal cord injuries (sci) lead to permanent irreversible functional deficits.  poor prognosis of patients is the motivation of searching a treatment for the chronic injury.  planting stem cells provides us with a promising strategy. in the meanwhile, the use of olfactory ensheathing cells (oecs) has shown very good results.  this study aims at evaluating the effect of transplante...