abstract   objective: to evaluate and review our experience with pediatric spinal injuries and factors affecting outcome, the authors conducted a retrospective clinical study of 43 cases (32 boys, 11 girls) of pediatric spine injuries treated during four years (january 1999 to december 2003).   methods: forty-three children with spinal injuries were studied retrospectively over four years and w...

Background: Spinal cord injury (SCI) refers to spinal cord damage arising from trauma, disease or degeneration. At present, there is still no treatment for any paraplegia resulting from SCI. We have previously shown that very low intensity, low frequency, electromagnetic field treatment (VLIFE) promotes neuronal plasticity after stroke and as a result, improves clinical recovery. Objective: In ...

Lhermitte's sign (LS) is a transient symptom consisting of an electric shock-like sensation radiating ascending along the spinal cord during forward flexion neck. It may be associated with sensory complaints such as hypo or hyperesthesia. Although it more common in cervical lesions, can also seen less frequently thoracic lesions. LS classified one paroxysmal pain syndromes multiple sclerosis (M...

the prevalence of spinal cord injury (sci) is about 2.5 million in the worldwide and more than 130,000 new injuries reported each year. regeneration in the cns versus the pns is very different from the other tissues and many factors can prevent regeneration in pns and specially cns. previous researches demonstrated that regeneration of cns can inhibit by inhibitory molecules and glial scar. the...

PURPOSE To 1) correlate spinal MR features and modes of clinical presentation associated with symptomatic neurologic deterioration following longstanding spinal trauma; 2) correlate degree of neurologic deficit with spinal MR appearance in these patients; and 3) determine the relationship between new symptoms and ongoing cord compression. METHODS Retrospective examination of MR images, and co...

This paper presents a novel biomechatronic device that resolves the necessities of mobility for people with spinal cord trauma (SCI) and disability. The proposed features safe reliable mechanism withstands daily use without premature mechanical wear, facilitating activities living (ADL) affected by SCI, integrating them to social workforce environment allows them, on one hand, move in standing ...

Activity-dependent plasticity occurs in the spinal cord throughout life. Driven by input from the periphery and the brain, this plasticity plays an important role in the acquisition and maintenance of motor skills and in the effects of spinal cord injury and other central nervous system disorders. The responses of the isolated spinal cord to sensory input display sensitization, long-term potent...

compound action potential (cap) of spinal cord represents valuable properties of neural fibers including excitability, rate of myelination and membrane integrity. these properties are measured using amplitude, latency and area under curve of caps recorded from spinal cord. here, the isolated spinal cord was set in a double sucrose gap (dsg) chamber and its response to intracellular stimulation ...

Dysfunction and death of spinal cord neurons are critical determinants of neurological deficits in various pathological conditions, including multiple sclerosis (MS) and spinal cord injury. Yet, the molecular mechanisms underlying neuronal/axonal damage remain undefined. Our previous studies raised the possibility that a decrease in the levels of plasma membrane calcium ATPase isoform 2 (PMCA2)...