نتایج جستجو برای: spindle tree
تعداد نتایج: 196672 فیلتر نتایج به سال:
Rat kangaroo kidney epithelium (PtK2) cells develop prominent asters and spindles during anaphase B of mitosis. It has been shown that severing the spindle at early anaphase B in living PtK1 cells results in a dramatic increase in the rate of pole-pole separation. This result suggested that the asters pull on the spindle poles, putting tension on the spindle, while the spindle acts as a governo...
Centrosomes represent the major microtubule organizing centers (MTOCs) of animal somatic cells and orchestrate bipolar spindle assembly during mitotic cell division. In meiotic cells, the kinesin HSET compensates for the lack of centrosomes by focusing acentrosomal MTOCs into two spindle poles. By clustering multiple centrosomes into two spindle poles, HSET also mediates bipolar mitosis in canc...
Isolated central spindles or spindles in detergent-permeabilized cells from the diatom Cylindrotheca fusiformis can undergo ATP-dependent reactivation of spindle elongation in vitro. We have used a peptide antibody raised against a 10-amino acid portion common to the kinesin superfamily motor domain to look for kinesin-like motor activity during anaphase B of mitosis. The peptide antibody local...
SSD (synchronized switch damping) is used for vibration control of the motorized spindle based on piezoelectric stack. Moreover, inspired by self-powered SSDI, a SSDV circuit was designed to overcome disadvantages requiring readjusting parameters and sensor re-positioning SSDI damping inductor) voltage source). A simulation an experimental were built, results show performance better than more f...
Sarcomatoid carcinoma is a type of spindle cell neoplasm. These varieties neoplasms comprise diverse collection benign and malignant neoplasms. carcinoma, also known by various other names such as Spindle Lane’s tumor, to name few, an exceedingly rare aggressive variant squamous 3, 7, 8 The variation in its nomenclature reflects the divergent interpretation sarcomatoid component reactive or neo...
We have identified an 80-kD protein that is involved in mitotic spindle elongation in the diatom Cylindrotheca fusiformis. DSK1 (Diatom Spindle Kinesin 1) was isolated using a peptide antibody raised against a conserved region in the motor domain of the kinesin superfamily. By sequence homology, DSK1 belongs to the central motor family of kinesin-related proteins. Immunoblots using an antibody ...
In both vertebrates and invertebrates, meiotic divisions in oocytes are typically asymmetric, resulting in the formation of a large oocyte and small polar bodies. The size difference between the daughter cells is usually a consequence of asymmetric positioning of the spindle before cytokinesis. Spindle movements are often related to interactions between the cell cortex and the spindle asters [1...
Chromosomes attain a metaphase position on half-spindles in the absence of an opposing spindle pole.
To examine the relative roles of chromosomes, spindle poles and microtubules in the formation of the metaphase spindle and metakinesis, I have experimentally placed an extra centrosome-free pronucleus close to a forming bipolar spindle in a living cell. The chromosomes from the extra nucleus induce the formation of an extra half-spindle from one pole of the otherwise normal bipolar spindle with...
The mitotic spindle is an essential molecular machine involved in cell division, whose composition has been studied extensively by detailed cellular biology, high-throughput proteomics, and RNA interference experiments. However, because of its dynamic organization and complex regulation it is difficult to obtain a complete description of its molecular composition. We have implemented an integra...
Oocyte meiotic spindles are associated with spindle-enriched mRNAs, phosphorylated ribosome protein S6, and phosphorylated variants of the key translational regulator, eukaryotic translation initiation factor 4E-binding protein 1 (eIF4E-BP1), consistent with translational control of localized mRNAs by eIF4E-BP1 in facilitating spindle formation and stability. Using specific kinase inhibitors, w...
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