نتایج جستجو برای: spion
تعداد نتایج: 289 فیلتر نتایج به سال:
Feraheme, is a recently FDA-cleared superparamagnetic iron oxide nanoparticle (SPION)-based MRI contrast agent that is also employed in the treatment of iron deficiency anemia. Feraheme nanoparticles have a hydrodynamic diameter of 30 nm and consist of iron oxide crystallites complexed with a low molecular weight, semi-synthetic carbohydrate. These features are attractive for other potential bi...
The prostate specific membrane antigen (PSMA) is broadly overexpressed on prostate cancer (PCa) cell surfaces. In this study, we report the synthesis, characterization, in vitro binding assay, and in vivo magnetic resonance imaging (MRI) evaluation of PSMA targeting superparamagnetic iron oxide nanoparticles (SPIONs). PSMA-targeting polypeptide CQKHHNYLC was conjugated to SPIONs to form PSMA-ta...
Introduction Cisplatin is one of the standard treatments head and neck tumors leading frequently to severe systemic side effects. This could be improved by targeted drug delivery with nanoparticles in combination local hyperthermia. Unfortunately, outcome studies on hyperthermia HNSCC are diverse. Therefore, we started testing effect nanoparticle uptake HNSCC-cell lines, their toxicity,
The increase in clinical trials assessing the efficacy of cell therapy for structural and functional regeneration of the nervous system in diseases related to the aging brain is well known. However, the results are inconclusive as to the best cell type to be used or the best methodology for the homing of these stem cells. This systematic review analyzed published data on SPION (superparamagneti...
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