Validation of pulse oximetry in commercially available normobaric hypoxic chambers (NHC) has not been previously reported. The present study examined the validity of pulse oximetry (SpO2) against direct measurements of arterial oxygen saturation (SaO2) via co-oximetry (AVOXimeter 4000) in 13 young adults age 21.3 +/- 0.6 years. Over a period of 2.5 hrs, the inspired fraction of oxygen inside a ...

We have investigated 296 inpatients in a single-blind observer study to determine the incidence, degree and duration of hypoxaemia during anaesthesia. The clinical recognition of hypoxaemia, period of time until recognition and risk factors were studied. Oxygen saturation (Spo2) was monitored continuously with a pulse oximeter (Ohmeda, model 3700). One or more episodes of mild hypoxaemia (Spo2 ...

Classification of cognitive workload promises immense benefit in diverse areas ranging from driver safety to augmenting human capability through closed loop brain computer interface. The is the most metabolically active organ body and increases its metabolic activity thus oxygen consumption with increasing demand. In this study, we explore feasibility in-ear SpO2 tracking. To end, preform asses...

Regional cerebral oxygenation (rSO2) and peripheral oxygen saturation (SpO2) have been studied in subjects inside a portable hyperbaric chamber at altitude during pressurization. The effects of the accumulation of carbon dioxide within the chamber on rSO2 and SpO2 have also been investigated. Three studies of cerebral regional oxygenation were undertaken, using near-IR spectroscopy, in subjects...

OBJECTIVE This study tested the effects of low perfusion caused by emerging sepsis on the reliability of a new pulse oximetry technology (Masimo SET; IVY 405T) compared with a standard pulse oximeter (Nellcor N-200). DESIGN Randomized trial. SETTING University animal research facility. SUBJECTS Twenty-six anesthetized, ventilated (Fio, 1.0), adult rabbits. INTERVENTIONS Pneumonia/sepsis...

OBJECTIVE: To test the hypothesis that a foam plastic insert that allows the infant head to rest in a neutral position in sleep may prevent obstruction of the upper airway and thus reduce episodes of reduced oxygenation in term infants in car seats. METHODS: Healthy full-term babies were randomized to be studied during sleep while restrained in an infant car safety seat either with or without t...

INTRODUCTION We developed a device (FreeO2) that automatically adjusts the oxygen flow rates based on patients' needs, in order to limit hyperoxia and hypoxemia and to automatically wean them from oxygen. OBJECTIVE The aim of this study was to evaluate the feasibility of using FreeO2 in patients hospitalized in the respiratory ward for an acute exacerbation of COPD. METHODS We conducted a r...

Splanchnic ischaemia can ultimately lead to cellular hypoxia and necrosis, and may well contribute to the development of multiple organ failures and increased mortality. Therefore, it is of utmost importance to monitor abdominal organ blood oxygen saturation (SpO2). Pulse oximetry has been widely accepted as a reliable method for monitoring oxygen saturation of arterial blood. Animal studies ha...

BACKGROUND We conducted this study to determine whether pulse oximetry and volumetric capnography (VCap) can determine the opening and closing pressures of lungs of anesthetized morbidly obese patients. METHODS Twenty morbidly obese patients undergoing laparoscopic bariatric surgery with capnoperitoneum were studied. A lung recruitment maneuver was performed in pressure control ventilation as...

BACKGROUND Because standard home oxygen (O2) systems deliver O2 at fixed rates, these systems are not designed to ensure optimal oxygen delivery based on physiologic need. We tested the ability of the AccuO2 (OptiSat Medical, Minneapolis, Minnesota), a portable, closed-loop, oximetry-driven, O2-conserving device to maintain SpO2 at ≥ 90%, compared to continuous-flow oxygen and a standard O2-con...