OBJECTIVES Neutrophil extracellular traps (NETs) have been visualized at the site of ANCA-associated vasculitis (AAV) lesions. Increased levels of NET remnants in the circulation have been reported in some AAV patients with active disease. The aim of the present study was to analyse NET remnants in a larger cohort of AAV patients with varying degrees of disease activity and to elucidate possibl...

pretibial myxedema is an uncommon manifestation of graves' disease and because of its rarity, information regarding its natural course and its relationship with other manifestations of graves' disease is not sufficient. we reviewed 150 consecutive cases diagnosed as having pretibial myxedema in a twenty-year period in a tertiary care center. only one patient in this group did not have ophthalmo...

asthma is the most common chronic disease in children. the natural history of asthma is often  characterized by periods  of  remission and  relapse. the  aim of  this study was to determine the remission rate of asthmatic children after entering the second decade of life and remission related factors in a hospital–based cohort. the  study  population  was  asthmatic  children  who  were  diagno...

Background:Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple organ involvement and periods of relapse and remission that mainly affects young women of childbearing age. In this regard the reproductive health is an important issue. Although diagnosis, treatment and management of pregnancy in SLE women have been improved recently, but the main concern is effects of SLE on ...

Graphical solutions of ordinary differential equations for simplified processes of heat flow in fluids (Lorenz system) and an idea of common mathematical description are the basis for the proposed thermodynamical leukemia model. The model provides description of remission and relapse in leukemia as two hierarchical states of normal hematopoiesis. Transition between them is possible through a pi...

OBJECTIVE Endometrial cancer with hematogenous metastases can be treated with chemotherapy. We present a case of spontaneous pneumothorax that occurred when a solitary pulmonary endometrial metastatic lesion was treated with paclitaxel plus carboplatin. CASE REPORT A 38-year-old female had stage II endometrial endometrioid adenocarcinoma. Solitary bilateral pulmonary metastases developed afte...

Membranous glomerulonephritis (MGN) represents an immunologically mediated disease characterized by deposition of immune complexes in the glomerular subepithelial space. Persistent proteinuria at diagnosis predicts poor prognosis. Pregnancy with MGN is a risk of fetal loss and may worsen maternal renal function.Here, we report a lady with MGN and proteinuria achieved spontaneous remission and s...