piroxicam, an anti-inflammatory drug, exhibits poor water solubility and flow properties, poor dissolution and poor wetting. consequently, the aim of this study was to improve the dissolution of piroxicam. microparticles containing piroxicam were produced by spray drying, using isopropyl alcohol and water in the ratio of 40:60 v/v as solvent system, and spray chilling technology by melting the ...

Social-cognitive deficits contribute to poor functional outcomes in early psychosis; however, no effective pharmacological treatments exist for these problems. This study was the first to investigate the efficacy of an extended treatment of oxytocin nasal spray combined with social cognition training (SCT) to improve social cognition, clinical symptoms, and social functioning in early psychosis...

OBJECTIVE The aim of this in vitro experimental study was to perform histological evaluation of the thermal effect produced on soft tissue irradiated with CO2, Er,Cr:YSGG or diode lasers. STUDY DESIGN Porcine oral mucosa samples were irradiated with Er,Cr:YSGG laser at 1 W with and without water / air spray, at 2 W with and without water / air spray, and at 4 W with water / air spray, with CO...

Large-eddy simulation of an atomizing spray issuing from a gas-turbine injector is performed. The filtered Navier–Stokes equations with dynamic subgrid scale model are solved on unstructured grids to compute the swirling turbulent flow through complex passages of the injector. The collocated grid, incompressible flow algorithm on arbitrary shaped unstructured grids developed by Mahesh et al. (J...

Turbulent multi-phase combustion is encountered in a number of engineering applications, such as internal combustion engines and gas-turbine aircraft engines. Therefore, the ability to perform accurate numerical simulations of these systems is of paramount importance to improve their design and efficiency. However, the underlying physics of spray combustion are extremely complicated. The liquid...

In spray painting applications, it is essential to generate a spray gun trajectory such that the entire surface is completely covered and receives an acceptably uniform layer of paint deposition; we call this the “uniform coverage” problem. The uniform coverage problem is challenging because the atomizer emits a non-trivial paint distribution, thus making the relationships between the spray gun...

Background. Postoperative sore throat is one of the major complaints of general anesthesia in the postanesthesia care unit. This prospective study investigated the preventive effect of ketorolac tromethamine spray in postendotracheal-intubation-induced sore throat after general anesthesia. Methods. Surgical patients undergoing general anesthesia with endotracheal intubation were recruited from ...